| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Deba_0092 | Deba_0532 | Deba_0092 | Deba_0532 | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR004839:IPR015424:IPR004838:IPR001176:IPR 015421; KEGG: dol:Dole_1584 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: A8ZZY8 Aminotransferase class I and II; PFAM: Aminotransferase class I and II. | NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: ank:AnaeK_0029 NAD(P)H dehydrogenase (quinone); PFAM: NAD(P)H dehydrogenase (quinone); SPTR: B4UKI1 NAD(P)H dehydrogenase (Quinone); PFAM: Flavodoxin-like fold. | 0.665 |
| Deba_0092 | lysA | Deba_0092 | Deba_1878 | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR004839:IPR015424:IPR004838:IPR001176:IPR 015421; KEGG: dol:Dole_1584 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: A8ZZY8 Aminotransferase class I and II; PFAM: Aminotransferase class I and II. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.481 |
| Deba_0531 | Deba_0532 | Deba_0531 | Deba_0532 | Methyltransferase type 11; InterPro IPR013216; KEGG: afw:Anae109_4101 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: A7HHT3 Methyltransferase type 11; PFAM: Methyltransferase domain. | NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: ank:AnaeK_0029 NAD(P)H dehydrogenase (quinone); PFAM: NAD(P)H dehydrogenase (quinone); SPTR: B4UKI1 NAD(P)H dehydrogenase (Quinone); PFAM: Flavodoxin-like fold. | 0.746 |
| Deba_0531 | Deba_0533 | Deba_0531 | Deba_0533 | Methyltransferase type 11; InterPro IPR013216; KEGG: afw:Anae109_4101 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: A7HHT3 Methyltransferase type 11; PFAM: Methyltransferase domain. | Protein of unknown function DUF88; InterPro IPR002790; KEGG: rfr:Rfer_1542 hypothetical protein; PFAM: protein of unknown function DUF88; SPTR: Q21Y79 Putative uncharacterized protein; PFAM: Protein of unknown function DUF88. | 0.693 |
| Deba_0531 | cysS | Deba_0531 | Deba_0534 | Methyltransferase type 11; InterPro IPR013216; KEGG: afw:Anae109_4101 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: A7HHT3 Methyltransferase type 11; PFAM: Methyltransferase domain. | COGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR015803:IPR015273:IPR009080:IPR014729:IPR 002308; KEGG: sfu:Sfum_1634 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; PRIAM: Cysteine--tRNA ligase; SPTR: A0LIR9 Cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.607 |
| Deba_0531 | ispDF | Deba_0531 | Deba_0535 | Methyltransferase type 11; InterPro IPR013216; KEGG: afw:Anae109_4101 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: A7HHT3 Methyltransferase type 11; PFAM: Methyltransferase domain. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.655 |
| Deba_0532 | Deba_0092 | Deba_0532 | Deba_0092 | NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: ank:AnaeK_0029 NAD(P)H dehydrogenase (quinone); PFAM: NAD(P)H dehydrogenase (quinone); SPTR: B4UKI1 NAD(P)H dehydrogenase (Quinone); PFAM: Flavodoxin-like fold. | Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR004839:IPR015424:IPR004838:IPR001176:IPR 015421; KEGG: dol:Dole_1584 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: A8ZZY8 Aminotransferase class I and II; PFAM: Aminotransferase class I and II. | 0.665 |
| Deba_0532 | Deba_0531 | Deba_0532 | Deba_0531 | NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: ank:AnaeK_0029 NAD(P)H dehydrogenase (quinone); PFAM: NAD(P)H dehydrogenase (quinone); SPTR: B4UKI1 NAD(P)H dehydrogenase (Quinone); PFAM: Flavodoxin-like fold. | Methyltransferase type 11; InterPro IPR013216; KEGG: afw:Anae109_4101 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: A7HHT3 Methyltransferase type 11; PFAM: Methyltransferase domain. | 0.746 |
| Deba_0532 | Deba_0533 | Deba_0532 | Deba_0533 | NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: ank:AnaeK_0029 NAD(P)H dehydrogenase (quinone); PFAM: NAD(P)H dehydrogenase (quinone); SPTR: B4UKI1 NAD(P)H dehydrogenase (Quinone); PFAM: Flavodoxin-like fold. | Protein of unknown function DUF88; InterPro IPR002790; KEGG: rfr:Rfer_1542 hypothetical protein; PFAM: protein of unknown function DUF88; SPTR: Q21Y79 Putative uncharacterized protein; PFAM: Protein of unknown function DUF88. | 0.773 |
| Deba_0532 | Deba_1376 | Deba_0532 | Deba_1376 | NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: ank:AnaeK_0029 NAD(P)H dehydrogenase (quinone); PFAM: NAD(P)H dehydrogenase (quinone); SPTR: B4UKI1 NAD(P)H dehydrogenase (Quinone); PFAM: Flavodoxin-like fold. | Flavoprotein WrbA; COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR008254:IPR010089; KEGG: eba:ebA2303 TrpR binding protein WrbA; PFAM: flavodoxin/nitric oxide synthase; SPTR: Q5P5L5 Flavoprotein wrbA; TIGRFAM: flavoprotein WrbA; PFAM: NADPH-dependent FMN reductase; TIGRFAM: NAD(P)H:quinone oxidoreductase, type IV. | 0.911 |
| Deba_0532 | Deba_1858 | Deba_0532 | Deba_1858 | NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: ank:AnaeK_0029 NAD(P)H dehydrogenase (quinone); PFAM: NAD(P)H dehydrogenase (quinone); SPTR: B4UKI1 NAD(P)H dehydrogenase (Quinone); PFAM: Flavodoxin-like fold. | Flavodoxin/nitric oxide synthase; COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR008254; KEGG: nth:Nther_0880 flavodoxin/nitric oxide synthase; PFAM: flavodoxin/nitric oxide synthase; SPTR: B2A899 Flavodoxin/nitric oxide synthase; PFAM: NADPH-dependent FMN reductase. | 0.911 |
| Deba_0532 | Deba_2422 | Deba_0532 | Deba_2422 | NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: ank:AnaeK_0029 NAD(P)H dehydrogenase (quinone); PFAM: NAD(P)H dehydrogenase (quinone); SPTR: B4UKI1 NAD(P)H dehydrogenase (Quinone); PFAM: Flavodoxin-like fold. | Sodium/hydrogen exchanger; COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR014729:IPR006153:IPR006016; KEGG: aoe:Clos_2091 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; UspA domain protein; SPTR: A8MIJ5 Sodium/hydrogen exchanger; PFAM: Universal stress protein family; Sodium/hydrogen exchanger family. | 0.655 |
| Deba_0532 | cysS | Deba_0532 | Deba_0534 | NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: ank:AnaeK_0029 NAD(P)H dehydrogenase (quinone); PFAM: NAD(P)H dehydrogenase (quinone); SPTR: B4UKI1 NAD(P)H dehydrogenase (Quinone); PFAM: Flavodoxin-like fold. | COGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR015803:IPR015273:IPR009080:IPR014729:IPR 002308; KEGG: sfu:Sfum_1634 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; PRIAM: Cysteine--tRNA ligase; SPTR: A0LIR9 Cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.680 |
| Deba_0532 | ispDF | Deba_0532 | Deba_0535 | NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: ank:AnaeK_0029 NAD(P)H dehydrogenase (quinone); PFAM: NAD(P)H dehydrogenase (quinone); SPTR: B4UKI1 NAD(P)H dehydrogenase (Quinone); PFAM: Flavodoxin-like fold. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.675 |
| Deba_0532 | lysA | Deba_0532 | Deba_1878 | NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: ank:AnaeK_0029 NAD(P)H dehydrogenase (quinone); PFAM: NAD(P)H dehydrogenase (quinone); SPTR: B4UKI1 NAD(P)H dehydrogenase (Quinone); PFAM: Flavodoxin-like fold. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.827 |
| Deba_0532 | ubiE | Deba_0532 | Deba_2806 | NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: ank:AnaeK_0029 NAD(P)H dehydrogenase (quinone); PFAM: NAD(P)H dehydrogenase (quinone); SPTR: B4UKI1 NAD(P)H dehydrogenase (Quinone); PFAM: Flavodoxin-like fold. | Ubiquinone/menaquinone biosynthesis methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.900 |
| Deba_0533 | Deba_0531 | Deba_0533 | Deba_0531 | Protein of unknown function DUF88; InterPro IPR002790; KEGG: rfr:Rfer_1542 hypothetical protein; PFAM: protein of unknown function DUF88; SPTR: Q21Y79 Putative uncharacterized protein; PFAM: Protein of unknown function DUF88. | Methyltransferase type 11; InterPro IPR013216; KEGG: afw:Anae109_4101 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: A7HHT3 Methyltransferase type 11; PFAM: Methyltransferase domain. | 0.693 |
| Deba_0533 | Deba_0532 | Deba_0533 | Deba_0532 | Protein of unknown function DUF88; InterPro IPR002790; KEGG: rfr:Rfer_1542 hypothetical protein; PFAM: protein of unknown function DUF88; SPTR: Q21Y79 Putative uncharacterized protein; PFAM: Protein of unknown function DUF88. | NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: ank:AnaeK_0029 NAD(P)H dehydrogenase (quinone); PFAM: NAD(P)H dehydrogenase (quinone); SPTR: B4UKI1 NAD(P)H dehydrogenase (Quinone); PFAM: Flavodoxin-like fold. | 0.773 |
| Deba_0533 | cysS | Deba_0533 | Deba_0534 | Protein of unknown function DUF88; InterPro IPR002790; KEGG: rfr:Rfer_1542 hypothetical protein; PFAM: protein of unknown function DUF88; SPTR: Q21Y79 Putative uncharacterized protein; PFAM: Protein of unknown function DUF88. | COGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR015803:IPR015273:IPR009080:IPR014729:IPR 002308; KEGG: sfu:Sfum_1634 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; PRIAM: Cysteine--tRNA ligase; SPTR: A0LIR9 Cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.712 |
| Deba_0533 | ispDF | Deba_0533 | Deba_0535 | Protein of unknown function DUF88; InterPro IPR002790; KEGG: rfr:Rfer_1542 hypothetical protein; PFAM: protein of unknown function DUF88; SPTR: Q21Y79 Putative uncharacterized protein; PFAM: Protein of unknown function DUF88. | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). | 0.702 |