STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0533Protein of unknown function DUF88; InterPro IPR002790; KEGG: rfr:Rfer_1542 hypothetical protein; PFAM: protein of unknown function DUF88; SPTR: Q21Y79 Putative uncharacterized protein; PFAM: Protein of unknown function DUF88. (438 aa)    
Predicted Functional Partners:
Deba_0532
NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: ank:AnaeK_0029 NAD(P)H dehydrogenase (quinone); PFAM: NAD(P)H dehydrogenase (quinone); SPTR: B4UKI1 NAD(P)H dehydrogenase (Quinone); PFAM: Flavodoxin-like fold.
  
    0.774
ispDF
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
       0.700
cysS
COGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR015803:IPR015273:IPR009080:IPR014729:IPR 002308; KEGG: sfu:Sfum_1634 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; PRIAM: Cysteine--tRNA ligase; SPTR: A0LIR9 Cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.699
Deba_0531
Methyltransferase type 11; InterPro IPR013216; KEGG: afw:Anae109_4101 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: A7HHT3 Methyltransferase type 11; PFAM: Methyltransferase domain.
       0.693
trmB
Putative methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.658
Deba_0536
Protein of unknown function DUF309; InterPro IPR005500; KEGG: dat:HRM2_21250 hypothetical protein; PFAM: protein of unknown function DUF309; SPTR: C0QDF9 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF309).
       0.552
Deba_0530
COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: similar to peroxisomal enoyl-coenzyme A hydratase-like protein; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: C9Y8M4 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial; PFAM: Enoyl-CoA hydratase/isomerase family.
       0.457
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
   0.422
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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