STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cysSCOGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR015803:IPR015273:IPR009080:IPR014729:IPR 002308; KEGG: sfu:Sfum_1634 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; PRIAM: Cysteine--tRNA ligase; SPTR: A0LIR9 Cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (483 aa)    
Predicted Functional Partners:
cysS-2
Cysteine synthase; COGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR005856:IPR002308:IPR001926:IPR009080:IPR 015803:IPR015273:IPR014729:IPR001216; KEGG: dal:Dalk_3820 cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; SPTR: B8FC88 Cysteine synthase; TIGRFAM: cysteine synthase; cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Str [...]
 
 
0.930
Deba_1177
COGs: COG1045 Serine acetyltransferase; InterPro IPR011004:IPR001451; KEGG: sfu:Sfum_2682 serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; PRIAM: Serine O-acetyltransferase; SPTR: A0LLQ8 Serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase.
 
  
 0.876
ispDF
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
       0.843
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec).
 
 
 0.772
leuS
COGs: COG0495 Leucyl-tRNA synthetase; InterProIPR015945:IPR013155:IPR001412:IPR014729:IPR 002302:IPR009008:IPR009080; KEGG: glo:Glov_2116 leucyl-tRNA synthetase; PFAM: tRNA synthetase valyl/leucyl anticodon-binding; Arginyl-tRNA synthetase, class Ic, core; SPTR: B3E3L3 Leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.760
hisS
COGs: COG0124 Histidyl-tRNA synthetase; InterProIPR015807:IPR006195:IPR004154:IPR002314:IPR 004516; KEGG: ppd:Ppro_1381 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein; PRIAM: Histidine--tRNA ligase; SPTR: A1ANS7 Histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; manually curated; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase.
  
 
 0.735
Deba_0533
Protein of unknown function DUF88; InterPro IPR002790; KEGG: rfr:Rfer_1542 hypothetical protein; PFAM: protein of unknown function DUF88; SPTR: Q21Y79 Putative uncharacterized protein; PFAM: Protein of unknown function DUF88.
     
 0.699
Deba_0532
NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: ank:AnaeK_0029 NAD(P)H dehydrogenase (quinone); PFAM: NAD(P)H dehydrogenase (quinone); SPTR: B4UKI1 NAD(P)H dehydrogenase (Quinone); PFAM: Flavodoxin-like fold.
  
    0.679
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 
 0.677
thrS
COGs: COG0441 Threonyl-tRNA synthetase; InterProIPR002320:IPR006195:IPR004154:IPR018163:IPR 018158:IPR012947:IPR002314; KEGG: dde:Dde_2639 threonyl-tRNA synthetase / Ser-tRNA(Thr) hydrolase; PFAM: tRNA synthetase class II (G H P and S); Threonyl/alanyl tRNA synthetase SAD; Anticodon-binding domain protein; SPTR: Q30Y11 Threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: threonyl-tRNA synthetase; Belongs to the class-II [...]
 
  
 0.669
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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