STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Deba_0540Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR013767:IPR000160:IPR001633:IPR000014:IPR 000700; KEGG: tmz:Tmz1t_3959 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; SPTR: C5S5K8 Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); T [...] (703 aa)    
Predicted Functional Partners:
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
 
 0.969
Deba_3177
Diguanylate cyclase with PAS/PAC sensor; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterProIPR000014:IPR000160:IPR003660:IPR013767:IPR 013655:IPR013656:IPR000700:IPR001610; KEGG: dar:Daro_1156 diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PRIAM: Diguanylate kinase; SMART: GGDEF domain containing protein; histidine kinase HAMP region domain protein; PAS domain containing protein; PA [...]
 
 
0.909
Deba_1323
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013656:IPR013767:IPR003661:IPR003594:IPR 001789:IPR005467:IPR000014:IPR000700:IPR004358:IPR003018:I PR001610:IPR011006:IPR009082; KEGG: dal:Dalk_0107 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; GAF domain protein; PAC repeat-containing protein; response [...]
  
 
 0.904
Deba_0503
Diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR001633:IPR000644:IPR000160; KEGG: drt:Dret_0176 diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; CBS domain containing protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: C8WZK3 Diguanylate cyclase/phosphodiesterase; TIGRFAM: diguanylate cyclase; PFAM: EAL domain; CBS domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
0.894
Deba_0541
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: dvm:DvMF_1514 diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: B8DLT6 Diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
0.893
Deba_0403
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013655:IPR013767:IPR003661:IPR 003594:IPR011006:IPR009082:IPR000014:IPR001610:IPR004358:I PR005467:IPR000700; KEGG: sfu:Sfum_3740 putative PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; ATP-binding region [...]
  
 
 0.878
Deba_0630
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003018:IPR003661:IPR003594:IPR 001789:IPR005467:IPR011006:IPR009082:IPR004358:IPR013656:I PR013767; KEGG: sfu:Sfum_3740 putative PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; PAS fold domain protein; GAF domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; re [...]
  
 
 0.833
Deba_3178
Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR006674:IPR003607; KEGG: hor:Hore_12730 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: B8CXK4 Metal dependent phosphohydrolase; PFAM: HD domain.
 
 
 
 0.820
Deba_3301
Metal dependent phosphohydrolase; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR006674:IPR003607; KEGG: dal:Dalk_3112 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; GAF domain protein; SMART: GAF domain protein; metal-dependent phosphohydrolase HD region; SPTR: B8FBP9 Metal dependent phosphohydrolase; PFAM: HD domain; GAF domain.
 
 
 
 0.816
Deba_0019
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR013767:IPR003018:IPR003661:IPR003594:IPR 001789:IPR005467:IPR000014:IPR011006:IPR009082:IPR019825:I PR004358; KEGG: dal:Dalk_2518 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; response regulator recei [...]
  
 
 0.784
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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