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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
Deba_0557COGs: COG0288 Carbonic anhydrase; InterPro IPR001765; KEGG: pca:Pcar_2939 carbonic anhydrase; PFAM: carbonic anhydrase; SPTR: Q3A0D3 Carbonic anhydrase; PFAM: Carbonic anhydrase. (260 aa)    
Predicted Functional Partners:
Deba_0008
Response regulator receiver protein; COGs: COG2116 Formate/nitrite family of transporter; InterPro IPR001789:IPR000292:IPR011006; KEGG: dal:Dalk_2167 response regulator receiver protein; PFAM: formate/nitrite transporter; response regulator receiver; SMART: response regulator receiver; SPTR: B8FF43 Response regulator receiver protein; PFAM: Formate/nitrite transporter; Response regulator receiver domain; TIGRFAM: formate/nitrite transporter.
  
  
 0.824
Deba_1240
Transferase hexapeptide repeat protein; COGs: COG0663 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR001451:IPR011004; KEGG: ank:AnaeK_1516 transferase hexapeptide repeat protein; SPTR: B4UK37 Transferase hexapeptide repeat protein; manually curated.
    
 
 0.777
Deba_3065
InterPro IPR011004; KEGG: dal:Dalk_5167 hexapaptide repeat-containing transferase; SPTR: B8FE56 Hexapaptide repeat-containing transferase.
    
 
 0.772
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
 
 0.512
Deba_0556
Excinuclease ABC C subunit domain protein; InterPro IPR000305; KEGG: cyh:Cyan8802_3969 group I intron endonuclease; PFAM: Excinuclease ABC C subunit domain protein; SMART: Excinuclease ABC C subunit domain protein; SPTR: C7QQW2 Group I intron endonuclease; PFAM: GIY-YIG catalytic domain; TIGRFAM: group I intron endonuclease.
 
     0.494
Deba_1258
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR015590:IPR001670:IPR018211:IPR016160:IPR 016162:IPR016161; KEGG: dal:Dalk_3586 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; iron-containing alcohol dehydrogenase; SPTR: B8FGP4 Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase.
  
  
 0.491
Deba_0036
Sulphate transporter; COGs: COG0659 Sulfate permease and related transporter (MFS superfamily); InterPro IPR011547:IPR002645; KEGG: dde:Dde_3641 sulfate permease; PFAM: sulphate transporter; Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Q30V62 Sulfate permease; PFAM: Sulfate transporter family; STAS domain; TIGRFAM: high affinity sulphate transporter 1.
 
  
 0.461
Deba_0360
Phosphoglycerate mutase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: gur:Gura_4185 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: A5G960 Phosphoglycerate mutase; PFAM: Phosphoglycerate mutase family; TIGRFAM: alpha-ribazole phosphatase.
 
  
 0.443
Deba_1152
COGs: COG0069 Glutamate synthase domain 2; InterProIPR002489:IPR000583:IPR006982:IPR002932:IPR 013785:IPR017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: D1CEN9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
  
 0.419
Deba_0390
Molybdopterin dinucleotide-binding region; COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006963:IPR006656:IPR006657:IPR009010; KEGG: dol:Dole_1621 nitrate reductase; PFAM: molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; SPTR: A9A025 Nitrate reductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
    0.409
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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