STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLGlutamate-1-semialdehyde-2,1-aminomutase; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814:IPR015424:IPR015421:IPR004639; KEGG: pca:Pcar_0266 glutamate-1-semialdehyde aminotransferase; PFAM: aminotransferase class-III; SPTR: Q3A7W5 Glutamate-1-semialdehyde 2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase. (427 aa)    
Predicted Functional Partners:
Deba_2958
Porphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731:IPR013785; KEGG: dol:Dole_1224 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: Porphobilinogen synthase; SPTR: A8ZY23 Delta-aminolevulinic acid dehydratase; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.990
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.985
Deba_1025
Aminotransferase class-III; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR015424:IPR005814:IPR015421; KEGG: nwi:Nwi_2388 aminotransferase class-III; PFAM: aminotransferase class-III; SPTR: Q3SPZ9 Aminotransferase; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.924
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.907
Deba_0815
uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR014777:IPR014776:IPR000878:IPR 003754:IPR003043; KEGG: sfu:Sfum_3201 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: A0LN72 Uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase.
 
  
 0.851
Deba_0578
Putative transcriptional regulator, AsnC family; COGs: COG1522 Transcriptional regulators; InterPro IPR011991; KEGG: dal:Dalk_4278 putative transcriptional regulator, AsnC family; SPTR: B8FMC0 Putative transcriptional regulator, AsnC family.
     
 0.799
Deba_0576
Diheme cytochrome c; InterPro IPR018588:IPR009056; KEGG: dde:Dde_1896 putative lipoprotein; PFAM: Dihaem cytochrome c; SPTR: Q310F3 Lipoprotein, putative; PFAM: Dihaem cytochrome c.
       0.773
Deba_0329
COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR016040:IPR006367; KEGG: sfu:Sfum_1588 siroheme synthase; SPTR: A0LIM3 Precorrin-2 dehydrogenase; TIGRFAM: siroheme synthase; TIGRFAM: siroheme synthase, N-terminal domain.
   
 0.711
Deba_1636
COGs: COG2875 Precorrin-4 methylase; InterPro IPR000878:IPR014777:IPR014776; KEGG: ppd:Ppro_1250 uroporphyrin-III C/tetrapyrrole methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: A1ANF1 Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases.
 
   
 0.548
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
    
 0.548
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: medium (60%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.