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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
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Deba_0587Cl- channel voltage-gated family protein; COGs: COG0038 Chloride channel protein EriC; InterPro IPR001807:IPR000644:IPR014743; KEGG: sfu:Sfum_2352 Cl-channel, voltage-gated family protein; PFAM: Cl- channel voltage-gated family protein; CBS domain containing protein; SMART: CBS domain containing protein; SPTR: A0LKT1 Cl-channel, voltage-gated family protein; PFAM: CBS domain; Voltage gated chloride channel. (603 aa)    
Predicted Functional Partners:
Deba_0318
TrkA-C domain protein; COGs: COG0471 Di- and tricarboxylate transporter; InterPro IPR004680:IPR006037:IPR016040; KEGG: dol:Dole_2399 TrkA domain-containing protein; PFAM: TrkA-C domain protein; Citrate transporter; SPTR: A8ZVL6 TrkA-C domain protein; PFAM: TrkA-C domain; Citrate transporter.
  
  
 0.661
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.656
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
     
 0.642
Deba_2577
Helicase domain protein; COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR014001:IPR001650:IPR000330:IPR014021; KEGG: sfu:Sfum_3846 helicase domain-containing protein; PFAM: helicase domain protein; SNF2-related protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: A0LQ13 Helicase domain protein; manually curated; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.
   
 0.585
Deba_0585
COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: dol:Dole_1973 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: A8ZT94 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme.
  
  
 0.566
Deba_1209
Polynucleotide adenylyltransferase region; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR001667:IPR003156:IPR000644:IPR002646; KEGG: sfu:Sfum_0679 polynucleotide adenylyltransferase region; PFAM: Polynucleotide adenylyltransferase region; CBS domain containing protein; phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SMART: CBS domain containing protein; SPTR: A0LG26 Polynucleotide adenylyltransferase region; PFAM: DHH family; DHHA1 domain; CBS domain; Poly A polymerase head domain; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
  
 0.557
Deba_2710
Class II aldolase/adducin family protein; COGs: COG0235 Ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303:IPR014710:IPR011051:IPR013096; KEGG: chl:Chy400_0637 class II aldolase/adducin family protein; PFAM: class II aldolase/adducin family protein; Cupin 2 conserved barrel domain protein; SPTR: B9LJP0 Class II aldolase/adducin family protein; PFAM: Cupin domain; Class II Aldolase and Adducin N-terminal domain.
 
   
 0.541
Deba_0455
Undecaprenyl-phosphate glucose phosphotransferase; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362:IPR016040:IPR017473:IPR017475; KEGG: mxa:MXAN_2922 sugar transferase; PFAM: sugar transferase; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Q1PWC3 Similar to capsular polysaccharide synthesis protein; TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: Bacterial sugar transferase; TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; e [...]
     
 0.538
Deba_0586
COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: dol:Dole_1974 histone deacetylase superfamily protein; PFAM: histone deacetylase superfamily; SPTR: A8ZT95 Histone deacetylase superfamily; PFAM: Histone deacetylase domain.
     
 0.535
Deba_2422
Sodium/hydrogen exchanger; COGs: COG0475 Kef-type K+ transport systems membrane components; InterPro IPR014729:IPR006153:IPR006016; KEGG: aoe:Clos_2091 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; UspA domain protein; SPTR: A8MIJ5 Sodium/hydrogen exchanger; PFAM: Universal stress protein family; Sodium/hydrogen exchanger family.
 
   
 0.532
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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