STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0598GAF sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR003018:IPR003661:IPR003594:IPR004358:IPR 005467; KEGG: dal:Dalk_2141 GAF sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; SPTR: Q1NPH4 Sensor protein; PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (415 aa)    
Predicted Functional Partners:
Deba_0597
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterProIPR001789:IPR013105:IPR011717:IPR001440:IPR 011006:IPR019734:IPR011990:IPR013026:IPR005829; KEGG: hch:HCH_04305 FOG: CheY-like receiver; PFAM: response regulator receiver; Tetratricopeptide TPR_2 repeat protein; Tetratricopeptide TPR_4; TPR repeat-containing protein; SMART: response regulator receiver; Tetratricopeptide repeat; SPTR: A6F3F5 CheY-like receiver protein; PFAM: Response regulator receiver domain; Tetratricopeptide repeat.
 
 
 0.976
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
 
0.947
Deba_0602
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR011006; KEGG: sat:SYN_01292 response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q2LX20 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; PFAM: Response regulator receiver domain.
 
 
 0.912
Deba_2017
COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789:IPR011006; KEGG: lip:LI1142 CheY-like receiver; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q1MP81 CheY-like receiver; PFAM: Response regulator receiver domain.
 
 
 0.897
Deba_2154
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR011006:IPR001789; KEGG: dal:Dalk_3262 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: B8FJ25 Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
 
 0.887
Deba_1232
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR011006; KEGG: hor:Hore_22620 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: B8D0S1 Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
 
 0.881
Deba_0691
Transcriptional regulator, XRE family; InterPro IPR001387:IPR011051:IPR010982:IPR013096; KEGG: sfu:Sfum_4068 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein; SPTR: A0LQN1 Transcriptional regulator, XRE family; PFAM: Cupin domain; Helix-turn-helix.
   
 
 0.868
Deba_1066
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR011006:IPR001789:IPR001867:IPR018480; KEGG: sfu:Sfum_0707 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: A0LG53 Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 0.850
Deba_2636
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003018:IPR003661:IPR003594:IPR009082:IPR 004358:IPR005467; KEGG: gur:Gura_0128 GAF sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; SPTR: A5GDK3 Sensor protein; PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
 0.821
Deba_0089
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013163:IPR013767:IPR003661:IPR003594:IPR 001789:IPR005467:IPR000014:IPR000700:IPR011006:IPR009082:I PR001610:IPR004358; KEGG: dol:Dole_3265 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; Cache type 2 domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator receiver; SPTR: A9 [...]
 
 
 0.806
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.