STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0599Protein of unknown function DUF88; COGs: COG1432 conserved hypothetical protein; InterPro IPR002790; KEGG: hmo:HM1_0800 hypothetical protein; PFAM: protein of unknown function DUF88; SPTR: B0TB28 Putative uncharacterized protein; PFAM: Protein of unknown function DUF88. (200 aa)    
Predicted Functional Partners:
Deba_0598
GAF sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR003018:IPR003661:IPR003594:IPR004358:IPR 005467; KEGG: dal:Dalk_2141 GAF sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; SPTR: Q1NPH4 Sensor protein; PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
     
 0.782
Deba_0597
COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterProIPR001789:IPR013105:IPR011717:IPR001440:IPR 011006:IPR019734:IPR011990:IPR013026:IPR005829; KEGG: hch:HCH_04305 FOG: CheY-like receiver; PFAM: response regulator receiver; Tetratricopeptide TPR_2 repeat protein; Tetratricopeptide TPR_4; TPR repeat-containing protein; SMART: response regulator receiver; Tetratricopeptide repeat; SPTR: A6F3F5 CheY-like receiver protein; PFAM: Response regulator receiver domain; Tetratricopeptide repeat.
       0.773
trmB
Putative methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
  
 0.631
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
   0.517
Deba_0600
Beta-lactamase domain protein; COGs: COG1234 Metal-dependent hydrolase of the beta-lactamase superfamily III; KEGG: dal:Dalk_3435 beta-lactamase domain protein; SPTR: B8FLH7 Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily.
     
 0.474
Deba_0601
PHP domain protein; COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR004013:IPR016195:IPR003141; KEGG: chy:CHY_2227 phosphotransferase domain-containing protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: Q3A9Z4 PHP domain protein; PFAM: PHP domain.
       0.470
Deba_0602
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR011006; KEGG: sat:SYN_01292 response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q2LX20 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; PFAM: Response regulator receiver domain.
       0.426
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR004532:IPR002547:IPR005121:IPR012340:IPR 020825:IPR005147:IPR016027:IPR009061:IPR005146; KEGG: sfu:Sfum_0429 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: A0LFC7 Phenylalanyl-tRNA synthetase beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synth [...]
     
 0.419
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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