Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Deba_0604ABC-3 protein; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: noc:Noc_2421 ABC Mn2+/Zn2+ transporter,inner membrane subunit; PFAM: ABC-3 protein; SPTR: C5SCP6 ABC-3 protein; PFAM: ABC 3 transport family. (293 aa)    
Predicted Functional Partners:
Deba_0603
ABC transporter related protein; COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: dal:Dalk_2384 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: C8R0H6 ABC transporter related protein; PFAM: ABC transporter.
 
 0.999
Deba_0518
Periplasmic solute binding protein; COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006127:IPR006128; KEGG: dal:Dalk_1551 periplasmic solute binding protein; PFAM: periplasmic solute binding protein; SPTR: B8FAF3 Periplasmic solute binding protein; PFAM: Periplasmic solute binding protein family; Belongs to the bacterial solute-binding protein 9 family.
 
 
 0.995
bioA
Adenosylmethionine-8-amino-7-oxononanoateaminotr ansferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
  
    0.549
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
       0.540
Deba_2019
Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481:IPR007167:IPR008988; KEGG: dal:Dalk_1640 ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; FeoA family protein; SPTR: B8FAP2 Ferric uptake regulator, Fur family; PFAM: FeoA domain; Ferric uptake regulator family; Belongs to the Fur family.
  
  
 0.540
Deba_0607
8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
       0.536
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
  
    0.534
Deba_0602
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR011006; KEGG: sat:SYN_01292 response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q2LX20 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; PFAM: Response regulator receiver domain.
     
 0.533
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
     
 0.528
Deba_0600
Beta-lactamase domain protein; COGs: COG1234 Metal-dependent hydrolase of the beta-lactamase superfamily III; KEGG: dal:Dalk_3435 beta-lactamase domain protein; SPTR: B8FLH7 Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily.
       0.482
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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