STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0691Transcriptional regulator, XRE family; InterPro IPR001387:IPR011051:IPR010982:IPR013096; KEGG: sfu:Sfum_4068 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; Cupin 2 conserved barrel domain protein; SMART: helix-turn-helix domain protein; SPTR: A0LQN1 Transcriptional regulator, XRE family; PFAM: Cupin domain; Helix-turn-helix. (432 aa)    
Predicted Functional Partners:
Deba_0066
COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterProIPR003018:IPR003594:IPR005467:IPR009082:IPR 004358; KEGG: sfu:Sfum_0281 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; SPTR: Q2YZR5 Sensor protein; PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
   
 
 0.920
Deba_1647
Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663:IPR011991; KEGG: dal:Dalk_4913 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; SMART: regulatory protein GntR HTH; SPTR: B8FDF8 Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain.
 
  
 0.753
Deba_1749
Response regulator receiver sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR001789:IPR003661:IPR003594:IPR011006:IPR 009082:IPR004358:IPR005467; KEGG: ote:Oter_3856 response regulator receiver sensor signal transduction histidine kinase; PFAM: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SPTR: B1ZZ58 Sensor protein; PFAM: Response regulator receiver d [...]
   
 
 0.716
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
  
  
 0.706
Deba_1323
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013656:IPR013767:IPR003661:IPR003594:IPR 001789:IPR005467:IPR000014:IPR000700:IPR004358:IPR003018:I PR001610:IPR011006:IPR009082; KEGG: dal:Dalk_0107 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; GAF domain protein; PAC repeat-containing protein; response [...]
  
  
 0.671
Deba_0598
GAF sensor signal transduction histidine kinase; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterProIPR003018:IPR003661:IPR003594:IPR004358:IPR 005467; KEGG: dal:Dalk_2141 GAF sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; SPTR: Q1NPH4 Sensor protein; PFAM: GAF domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
   
 
 0.670
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.648
Deba_0479
COGs: COG0077 Prephenate dehydratase; InterProIPR020822:IPR001086:IPR002912:IPR008242:IPR 002701:IPR018528; KEGG: pca:Pcar_1887 chorismate mutase-P and prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Q1K0T9 Chorismate mutase; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
  
  
 0.647
Deba_1258
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR015590:IPR001670:IPR018211:IPR016160:IPR 016162:IPR016161; KEGG: dal:Dalk_3586 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; iron-containing alcohol dehydrogenase; SPTR: B8FGP4 Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase.
 
  
 0.626
Deba_0403
PAS/PAC sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013655:IPR013767:IPR003661:IPR 003594:IPR011006:IPR009082:IPR000014:IPR001610:IPR004358:I PR005467:IPR000700; KEGG: sfu:Sfum_3740 putative PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; histidine kinase A domain protein; ATP-binding region [...]
     
 0.624
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.