STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Deba_0693FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR004099:IPR016156:IPR013027:IPR000815:IPR 012999; KEGG: rxy:Rxyl_1767 mercuric reductase MerA; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: B4D639 Pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain. (456 aa)    
Predicted Functional Partners:
Deba_2980
Catalytic domain of components of various dehydrogenase complexes; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterProIPR000089:IPR004167:IPR001078:IPR011053:IPR 003016; KEGG: rha:RHA1_ro11029 dihydrolipoyllysine-residue succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: Q0RVL0 Dihydrolipoyllysine-residue succinyltransferase; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 bi [...]
 0.991
Deba_2979
Transketolase domain protein; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterProIPR005475:IPR005476:IPR015941:IPR009014:IPR 013838; KEGG: sso:SSO1526 pyruvate dehydrogenase beta subunit (lipoamide); PFAM: Transketolase domain protein; Transketolase central region; SPTR: B7S015 Transketolase, C-terminal domain protein; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
 
 0.987
Deba_2978
Dehydrogenase E1 component; COGs: COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type alpha subunit; InterPro IPR001017:IPR018370; KEGG: rxy:Rxyl_0348 pyruvate dehydrogenase (lipoamide); PFAM: dehydrogenase E1 component; SPTR: B7S016 Dehydrogenase E1 component superfamily protein; PFAM: Dehydrogenase E1 component.
 
 
 0.945
Deba_2141
Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterProIPR016040:IPR015884:IPR012188:IPR012301:IPR 012302:IPR002505; KEGG: glo:Glov_1262 malic enzyme; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; SPTR: B3E7A4 Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase; PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase.
  
  
 0.817
lipB-2
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the LipB family.
 
  
 0.783
Deba_0694
Protein of unknown function DUF21; COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR002550; KEGG: dps:DP2605 hypothetical protein; PFAM: protein of unknown function DUF21; CBS domain containing protein; SPTR: Q6AJZ2 Putative uncharacterized protein; PFAM: CBS domain; Domain of unknown function DUF21.
       0.773
Deba_3039
COGs: COG0095 Lipoate-protein ligase A; InterPro IPR004143:IPR002829; KEGG: mta:Moth_0443 biotin/lipoate A/B protein ligase; PFAM: biotin/lipoate A/B protein ligase; protein of unknown function DUF116; SPTR: Q2RLB5 Biotin/lipoate A/B protein ligase; PFAM: Protein of unknown function DUF116; Biotin/lipoate A/B protein ligase family; TIGRFAM: lipoyltransferase and lipoate-protein ligase.
 
 
 0.768
Deba_2986
COGs: COG0095 Lipoate-protein ligase A; InterPro IPR004143:IPR000923; KEGG: tro:trd_0142 hypothetical protein; PFAM: biotin/lipoate A/B protein ligase; SPTR: A8UQP5 Putative uncharacterized protein; PFAM: Bacterial lipoate protein ligase C-terminus; Biotin/lipoate A/B protein ligase family.
 
 
 0.757
Deba_0067
Redoxin domain protein; InterPro IPR013740:IPR017936:IPR012336:IPR012335; KEGG: afe:Lferr_0206 redoxin domain protein; PFAM: Redoxin domain protein; SPTR: C6MAN3 Thioredoxin family protein; PFAM: Redoxin.
  
 0.738
Deba_1369
Thioredoxin domain-containing protein; InterPro IPR012335:IPR012336; KEGG: sfu:Sfum_3604 thioredoxin domain-containing protein; SPTR: A0LPC2 Thioredoxin domain; PFAM: Thioredoxin.
  
 0.738
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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