STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Deba_0702HAD-superfamily hydrolase, subfamily IA, variant 3; COGs: COG0546 phosphatase; InterPro IPR006402:IPR006439:IPR005834; KEGG: dvm:DvMF_0135 haloacid dehalogenase domain protein hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: B8DNN9 Haloacid dehalogenase domain protein hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfami [...] (210 aa)    
Predicted Functional Partners:
Deba_1536
D-lactate dehydrogenase (cytochrome); COGs: COG0277 FAD/FMN-containing dehydrogenase; InterProIPR016166:IPR016164:IPR006094:IPR004113:IPR 016167:IPR016168:IPR000542; KEGG: dat:HRM2_18570 GlcD2; PFAM: FAD linked oxidase domain protein; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: C0QBU7 GlcD2; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD.
    
 0.910
Deba_1537
Protein of unknown function DUF224 cysteine-rich region domain protein; COGs: COG0247 Fe-S oxidoreductase; InterProIPR009051:IPR004017:IPR012285:IPR017896:IPR 017900; KEGG: gem:GM21_0576 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: C6DZR8 Putative uncharacterized protein; PFAM: Cysteine-rich domain.
    
 0.905
Deba_2213
HAD-superfamily hydrolase, subfamily IA, variant 1; COGs: COG0546 phosphatase; InterPro IPR005833:IPR005834:IPR006439; KEGG: dal:Dalk_3700 HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: B8FLN4 HAD-superfamily hydrolase, subfamily IA, variant 1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif [...]
     
  0.900
Deba_0703
Molybdopterin binding domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
  
    0.798
Deba_0705
Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216:IPR017441; KEGG: dol:Dole_1525 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: A8ZZS9 Methyltransferase type 11; PFAM: Methyltransferase domain.
   
 
 0.780
Deba_0704
COGs: COG2191 Formylmethanofuran dehydrogenase subunit E; InterPro IPR003814; KEGG: aba:Acid345_0503 formylmethanofuran dehydrogenase, subunit E; PFAM: formylmethanofuran dehydrogenase subunit E region; SPTR: Q1IUE2 Formylmethanofuran dehydrogenase, subunit E; PFAM: FmdE, Molybdenum formylmethanofuran dehydrogenase operon.
       0.773
Deba_0438
Dinitrogenase iron-molybdenum cofactor biosynthesis protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197:IPR003731; KEGG: dsa:Desal_0442 dinitrogenase iron-molybdenum cofactor biosynthesis protein; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; Radical SAM domain protein; SPTR: C6BX29 Dinitrogenase iron-molybdenum cofactor biosynthesis protein; PFAM: Radical SAM superfamily; Dinitrogenase iron-molybdenum cofactor.
  
    0.548
Deba_2210
Radical SAM domain protein; COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterPro IPR007197; KEGG: sfu:Sfum_1766 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SPTR: A0LJ51 Radical SAM domain protein; PFAM: Radical SAM superfamily.
  
    0.548
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
  
    0.548
Deba_0706
KEGG: mxa:MXAN_4033 hypothetical protein; SPTR: Q1D561 Putative uncharacterized protein.
       0.540
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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