STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (313 aa)    
Predicted Functional Partners:
Deba_0224
Transketolase; COGs: COG0021 Transketolase; InterProIPR005474:IPR005475:IPR005476:IPR009014:IPR 005478:IPR015941; KEGG: pna:Pnap_4499 transketolase; PFAM: Transketolase domain protein; Transketolase central region; SPTR: A6C7Q1 Transketolase; TIGRFAM: transketolase; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; Belongs to the transketolase family.
   
 
 0.963
Deba_2979
Transketolase domain protein; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterProIPR005475:IPR005476:IPR015941:IPR009014:IPR 013838; KEGG: sso:SSO1526 pyruvate dehydrogenase beta subunit (lipoamide); PFAM: Transketolase domain protein; Transketolase central region; SPTR: B7S015 Transketolase, C-terminal domain protein; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
  
 0.959
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 0.942
Deba_2385
COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500:IPR000276:IPR004785; KEGG: sfu:Sfum_1376 RpiB/LacA/LacB family sugar-phosphate isomerase; PFAM: Ribose/galactose isomerase; SPTR: A0LI15 Ribose-5-phosphate isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family.
  
 
 0.941
Deba_2980
Catalytic domain of components of various dehydrogenase complexes; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterProIPR000089:IPR004167:IPR001078:IPR011053:IPR 003016; KEGG: rha:RHA1_ro11029 dihydrolipoyllysine-residue succinyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: Q0RVL0 Dihydrolipoyllysine-residue succinyltransferase; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 bi [...]
   
 0.934
Deba_2695
Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; COGs: COG1109 Phosphomannomutase; InterProIPR016066:IPR016055:IPR005844:IPR005845:IPR 005846:IPR005843:IPR005841; KEGG: sfu:Sfum_0481 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase; SPTR: A0LFH9 Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/pho [...]
  
 0.929
rplY
Ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
  
  
 0.924
Deba_0509
NUDIX hydrolase; InterPro IPR000086:IPR015797:IPR020084; KEGG: rmr:Rmar_0039 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: D0MK35 NUDIX hydrolase; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family.
    
 0.912
Deba_2159
Transketolase domain protein; COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: sus:Acid_0656 transketolase domain-containing protein; PFAM: Transketolase domain protein; SPTR: Q02BA9 Transketolase domain protein; PFAM: Transketolase, thiamine diphosphate binding domain.
    
 0.911
Deba_2160
Transketolase central region; COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR009014:IPR005475; KEGG: sus:Acid_0657 transketolase, central region; PFAM: Transketolase central region; SPTR: Q02BA8 Transketolase, central region; manually curated; PFAM: Transketolase, pyrimidine binding domain.
    
  0.908
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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