STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
Deba_0763Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (289 aa)    
Predicted Functional Partners:
Deba_1872
2-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: xac:XAC1784 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: B7A5Y7 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFA [...]
 
 0.999
Deba_0817
FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR001645:IPR013221:IPR004101; KEGG: sfu:Sfum_1671 FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; PRIAM: Tetrahydrofolate synthase; SPTR: A0LIV6 FolC bifunctional protein; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase.
 
 0.997
Deba_3118
Aminotransferase class IV; COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544; KEGG: bba:Bd1736 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; SPTR: Q6MMA2 Branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV.
  
 
 0.929
Deba_0393
Beta-lactamase; COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: rpd:RPD_2374 beta-lactamase-like; SPTR: Q137Y3 Beta-lactamase-like; PFAM: Metallo-beta-lactamase superfamily.
     
 0.911
Deba_2677
Beta-lactamase domain protein; COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: adg:Adeg_1793 beta-lactamase domain protein; SPTR: C9R9A2 Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily.
     
 0.911
ftsH
ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
  
 0.882
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
  
  
 0.871
Deba_3186
COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterProIPR005802:IPR005801:IPR001544:IPR006805:IPR 015890:IPR019999; KEGG: dat:HRM2_08090 PabB; PFAM: Chorismate binding-like; Anthranilate synthase component I domain protein; aminotransferase class IV; SPTR: C0QJR9 PabB; TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Aminotransferase class IV; Anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade.
 
  
 0.850
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
       0.795
dacA
Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.
       0.795
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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