STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaXTranscriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (255 aa)    
Predicted Functional Partners:
panC
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 
 0.970
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
 
  
 0.951
Deba_1219
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
 
 
 0.944
Deba_0953
MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518:IPR011551; KEGG: scl:sce4803 hypothetical protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: A9FF91 Putative uncharacterized protein mazG; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein.
   
 
  0.905
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.890
Deba_0768
Peptidase U61 LD-carboxypeptidase A; COGs: COG1619 conserved hypothetical protein; InterPro IPR003507; KEGG: ade:Adeh_3395 peptidase S66, LD-carboxypeptidase A; PFAM: peptidase U61 LD-carboxypeptidase A; SPTR: Q2IF02 Peptidase S66, LD-carboxypeptidase A; PFAM: LD-carboxypeptidase.
       0.795
Deba_0769
COGs: COG1680 Beta-lactamase class C and other penicillin binding protein; InterPro IPR012338:IPR001466; KEGG: dol:Dole_0591 beta-lactamase; PFAM: beta-lactamase; SPTR: A8ZU89 Beta-lactamase; PFAM: Beta-lactamase.
       0.793
Deba_0770
Mur ligase middle domain protein; COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR016040:IPR013221:IPR004101:IPR000713; KEGG: dps:DP2930 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diamino pimelate ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: Q1NLI3 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diaminopimelate ligase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diam [...]
       0.792
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
       0.730
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
  
  
 0.729
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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