STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0770Mur ligase middle domain protein; COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR016040:IPR013221:IPR004101:IPR000713; KEGG: dps:DP2930 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diamino pimelate ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: Q1NLI3 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diaminopimelate ligase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diam [...] (483 aa)    
Predicted Functional Partners:
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
 
  
 0.937
murF
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
 
  
 0.919
Deba_0769
COGs: COG1680 Beta-lactamase class C and other penicillin binding protein; InterPro IPR012338:IPR001466; KEGG: dol:Dole_0591 beta-lactamase; PFAM: beta-lactamase; SPTR: A8ZU89 Beta-lactamase; PFAM: Beta-lactamase.
 
   
 0.861
Deba_0768
Peptidase U61 LD-carboxypeptidase A; COGs: COG1619 conserved hypothetical protein; InterPro IPR003507; KEGG: ade:Adeh_3395 peptidase S66, LD-carboxypeptidase A; PFAM: peptidase U61 LD-carboxypeptidase A; SPTR: Q2IF02 Peptidase S66, LD-carboxypeptidase A; PFAM: LD-carboxypeptidase.
 
   
 0.851
murD
UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
  
0.851
mraY
phospho-N-acetylmuramoyl-pentapeptide-transferas e; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.839
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
 
 
 0.826
Deba_2796
Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein.
  
  
 0.826
Deba_2792
COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182:IPR018365:IPR013437; KEGG: mxa:MXAN_5605 cell cycle protein FtsW; PFAM: cell cycle protein; SPTR: Q1D0S9 Cell cycle protein, FtsW/RodA/SpoVE family; TIGRFAM: cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA; cell division protein FtsW; Belongs to the SEDS family.
 
  
 0.824
coaX
Transcriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
       0.792
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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