STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
icmFmethylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1093 aa)    
Predicted Functional Partners:
Deba_0883
Cobalamin B12-binding domain protein; COGs: COG2185 Methylmalonyl-CoA mutase C-terminal domain/subunit (cobalamin-binding); InterPro IPR006159:IPR006158; KEGG: pth:PTH_1362 methylmalonyl-CoA mutase C-terminal domain-containing protein; PFAM: cobalamin B12-binding domain protein; SPTR: A5D2I7 Methylmalonyl-CoA mutase, C-terminal domain/subunit; PFAM: B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain.
 
0.993
Deba_0882
COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006098:IPR014348:IPR016176:IPR006099; KEGG: tex:Teth514_1855 methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; PRIAM: Methylmalonyl-CoA mutase; SPTR: C7IS99 Methylmalonyl-CoA mutase, large subunit; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain.
 
 
0.963
Deba_1287
LAO/AO transport system ATPase; COGs: COG1703 Putative periplasmic protein kinase ArgK and related GTPase of G3E family; InterPro IPR005129:IPR003593; KEGG: ppd:Ppro_0389 LAO/AO transport system ATPase; PFAM: ArgK protein; SMART: AAA ATPase; SPTR: A1AL03 LAO/AO transport system ATPase; TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; TIGRFAM: LAO/AO transport system ATPase.
 
  
0.914
Deba_0777
Transcriptional regulator, TetR family; InterPro IPR001647:IPR012287:IPR009057; KEGG: dal:Dalk_2753 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: B8FKS3 Transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family.
 
 
 
 0.864
Deba_0690
methylmalonyl-CoA epimerase; InterPro IPR017515:IPR004360; KEGG: sfu:Sfum_0455 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: A0LFF3 Methylmalonyl-CoA epimerase; TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase.
 
  
 0.860
Deba_0084
GCN5-related N-acetyltransferase; COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702:IPR000182:IPR016181; KEGG: dat:HRM2_05020 putative 4-hydroxybutyrate CoA-transferase; PFAM: GCN5-related N-acetyltransferase; acetyl-CoA hydrolase/transferase; SPTR: C0QHQ8 Putative 4-hydroxybutyrate CoA-transferase; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain; Acetyltransferase (GNAT) family.
  
  
 0.838
Deba_0155
GCN5-related N-acetyltransferase; COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702:IPR000182:IPR016181; KEGG: sfu:Sfum_0746 acetyl-CoA hydrolase/transferase; PFAM: GCN5-related N-acetyltransferase; acetyl-CoA hydrolase/transferase; SPTR: A0LG92 Acetyl-CoA hydrolase/transferase; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain; Acetyltransferase (GNAT) family.
  
  
 0.838
Deba_0710
COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702; KEGG: mhu:Mhun_1561 acetyl-CoA hydrolase/transferase; PFAM: acetyl-CoA hydrolase/transferase; SPTR: Q2FRF0 Acetyl-CoA hydrolase/transferase; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain.
  
  
 0.808
Deba_3272
COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702; KEGG: dhd:Dhaf_2858 acetyl-CoA hydrolase/transferase; PFAM: acetyl-CoA hydrolase/transferase; SPTR: Q24WU2 Putative uncharacterized protein; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain.
  
  
 0.808
Deba_3273
COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702; KEGG: drm:Dred_1489 acetyl-CoA hydrolase/transferase; PFAM: acetyl-CoA hydrolase/transferase; SPTR: A4J4L6 Acetyl-CoA hydrolase/transferase; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain.
  
  
 0.808
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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