STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0777Transcriptional regulator, TetR family; InterPro IPR001647:IPR012287:IPR009057; KEGG: dal:Dalk_2753 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: B8FKS3 Transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family. (212 aa)    
Predicted Functional Partners:
icmF
methylmalonyl-CoA mutase, large subunit; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.
 
 
 
 0.864
Deba_2882
Transcriptional regulator, TetR family; COGs: COG1309 Transcriptional regulator; InterProIPR001647:IPR013570:IPR012287:IPR015893:IPR 011075:IPR009057; KEGG: sfu:Sfum_1401 TetR family transcriptional regulator; PFAM: regulatory protein TetR; Tetracycline transcriptional regulator YsiA domain protein; SPTR: C8QXS1 Transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family; YsiA-like protein, C-terminal region.
  
     0.543
Deba_1782
InterPro IPR009057:IPR001647:IPR012287; KEGG: mpt:Mpe_A2962 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: C5SCW5 Transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family.
  
     0.482
Deba_2819
Transcriptional regulator, TetR family; COGs: COG1309 Transcriptional regulator; InterPro IPR001647:IPR012287:IPR009057:IPR011075; KEGG: scl:sce1733 HTH-type transcriptional regulator AcrR; PFAM: regulatory protein TetR; SPTR: A9FIV1 HTH-type transcriptional regulator acrR; PFAM: Bacterial regulatory proteins, tetR family.
  
     0.481
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
   
 
 0.435
Deba_3193
Transcriptional regulator, TetR family; InterPro IPR009057:IPR011075:IPR001647:IPR012287; KEGG: dal:Dalk_1849 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: B8FFZ1 Transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family.
  
     0.417
Deba_1373
KEGG: dps:DP0753 hypothetical protein; SPTR: C8QY26 Putative uncharacterized protein.
  
     0.412
Deba_1863
COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterProIPR017441:IPR006176:IPR006108:IPR001753:IPR 016040:IPR008927:IPR013328; KEGG: chy:CHY_1609 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase/isomerase family protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase NAD-binding; 3-hydroxyacyl-CoA dehydrogenase domain protein; Enoyl-CoA hydratase/isomerase; SPTR: Q3ABP7 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase/isomerase family protein; PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain.
 
  
 0.412
Deba_3065
InterPro IPR011004; KEGG: dal:Dalk_5167 hexapaptide repeat-containing transferase; SPTR: B8FE56 Hexapaptide repeat-containing transferase.
  
 
   0.410
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
   
    0.408
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (26%) [HD]