STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0797KEGG: ppd:Ppro_2085 hypothetical protein; SPTR: A1AQS3 Putative uncharacterized protein. (332 aa)    
Predicted Functional Partners:
Deba_0798
Iron-containing alcohol dehydrogenase; COGs: COG0371 Glycerol dehydrogenase; InterPro IPR001670:IPR016160:IPR018211:IPR016205; KEGG: sth:STH1267 glycerol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: C1TM17 Glycerol dehydrogenase-like oxidoreductase; PFAM: Iron-containing alcohol dehydrogenase.
       0.565
Deba_0796
Conserved hypothetical protein; InterPro IPR020080:IPR013838; KEGG: ppd:Ppro_2085 hypothetical protein; SPTR: A1AQS3 Putative uncharacterized protein.
      
0.524
Deba_2278
COGs: COG0681 Signal peptidase I; InterProIPR015927:IPR000223:IPR011056:IPR019756:IPR 019757:IPR019758:IPR019759; KEGG: dvm:DvMF_2718 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: B8DIZ6 Signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; Belongs to the peptidase S26 family.
   
    0.503
Deba_1961
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
    0.480
Deba_0383
COGs: COG0704 Phosphate uptake regulator; InterPro IPR008170:IPR002575:IPR011009; KEGG: dma:DMR_33380 hypothetical protein; PFAM: PhoU family protein; aminoglycoside phosphotransferase; SPTR: C4XK89 Putative uncharacterized protein; PFAM: Domain of unknown function (DUF227); PhoU domain.
   
    0.448
Deba_1065
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
   
    0.448
Deba_0696
NAD-dependent epimerase/dehydratase; COGs: COG1090 nucleoside-diphosphate sugar epimerase; InterProIPR010099:IPR016040:IPR001509:IPR013549:IPR 003006; KEGG: dal:Dalk_2593 domain of unknown function DUF1731; PFAM: NAD-dependent epimerase/dehydratase; domain of unknown function DUF1731; SPTR: Q1NNH6 Putative uncharacterized protein; PFAM: NAD dependent epimerase/dehydratase family; Domain of unknown function (DUF1731); TIGRFAM: conserved hypothetical protein TIGR01777.
   
    0.426
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
    0.424
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
  
 0.422
tpx
Redoxin domain protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
   
    0.416
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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