Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0806Glycoside hydrolase family 3 domain protein; COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764:IPR017853; KEGG: ank:AnaeK_4399 glycoside hydrolase family 3 domain protein; PFAM: glycoside hydrolase family 3 domain protein; SPTR: Q1NXP1 Glycoside hydrolase, family 3-like; PFAM: Glycosyl hydrolase family 3 N terminal domain. (352 aa)    
Predicted Functional Partners:
Deba_0769
COGs: COG1680 Beta-lactamase class C and other penicillin binding protein; InterPro IPR012338:IPR001466; KEGG: dol:Dole_0591 beta-lactamase; PFAM: beta-lactamase; SPTR: A8ZU89 Beta-lactamase; PFAM: Beta-lactamase.
  
 0.963
Deba_3147
COGs: COG3876 conserved hypothetical protein; InterPro IPR008302; KEGG: dal:Dalk_0937 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: Q1NMF7 Uncharacterised conserved protein UCP016719; PFAM: Protein of unknown function (DUF1343).
 
  
 0.808
Deba_0807
Hypothetical protein; KEGG: mar:MAE_45780 magnesium protoporphyrin IX chelatase subunit D; SPTR: A8YEX0 Similar to Q4BXZ0_CROWT Magnesium chelatase.
       0.786
Deba_1816
Site-specific DNA-methyltransferase (adenine-specific); COGs: COG3392 Adenine-specific DNA methylase; InterPro IPR002052:IPR002294:IPR012327; KEGG: dde:Dde_0922 adenine-specific DNA methylase-like protein; PFAM: D12 class N6 adenine-specific DNA methyltransferase; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: Q314C3 Adenine-specific DNA methylase-like; PFAM: D12 class N6 adenine-specific DNA methyltransferase.
  
  
 0.733
Deba_0809
COGs: COG3178 phosphotransferase related to Ser/Thr protein kinase; InterPro IPR011009:IPR002575; KEGG: dps:DP2940 hypothetical protein; PFAM: aminoglycoside phosphotransferase; SPTR: C8QX22 Aminoglycoside phosphotransferase; PFAM: Phosphotransferase enzyme family.
 
   
 0.692
Deba_0808
Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR011004:IPR005835:IPR018357; KEGG: ank:AnaeK_3750 nucleotidyl transferase; PFAM: Nucleotidyl transferase; SPTR: B4UE03 Nucleotidyl transferase; PFAM: Nucleotidyl transferase.
 
   
 0.661
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
 
  
 0.591
Deba_0770
Mur ligase middle domain protein; COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR016040:IPR013221:IPR004101:IPR000713; KEGG: dps:DP2930 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diamino pimelate ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: Q1NLI3 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diaminopimelate ligase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso- diam [...]
 
   
 0.560
der
Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
       0.507
Deba_0768
Peptidase U61 LD-carboxypeptidase A; COGs: COG1619 conserved hypothetical protein; InterPro IPR003507; KEGG: ade:Adeh_3395 peptidase S66, LD-carboxypeptidase A; PFAM: peptidase U61 LD-carboxypeptidase A; SPTR: Q2IF02 Peptidase S66, LD-carboxypeptidase A; PFAM: LD-carboxypeptidase.
 
   
 0.503
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (22%) [HD]