STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0815uroporphyrin-III C-methyltransferase; COGs: COG0007 Uroporphyrinogen-III methylase; InterProIPR006366:IPR014777:IPR014776:IPR000878:IPR 003754:IPR003043; KEGG: sfu:Sfum_3201 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: A0LN72 Uroporphyrinogen-III synthase / uroporphyrinogen-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. (509 aa)    
Predicted Functional Partners:
Deba_0329
COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR016040:IPR006367; KEGG: sfu:Sfum_1588 siroheme synthase; SPTR: A0LIM3 Precorrin-2 dehydrogenase; TIGRFAM: siroheme synthase; TIGRFAM: siroheme synthase, N-terminal domain.
 
 0.999
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 0.999
Deba_2958
Porphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731:IPR013785; KEGG: dol:Dole_1224 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: Porphobilinogen synthase; SPTR: A8ZY23 Delta-aminolevulinic acid dehydratase; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.995
Deba_2458
COGs: COG2243 Precorrin-2 methylase; InterPro IPR006364:IPR014777:IPR000878:IPR012382; KEGG: sfu:Sfum_2135 precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: A0LK65 Precorrin-2 C20-methyltransferase / cobalt-factor II C20-methyltransferase; TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase.
 
 
 0.968
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.948
Deba_3122
COGs: COG0755 ABC-type transport system involved in cytochrome c biogenesis permease component; InterPro IPR017562:IPR002541:IPR003557; KEGG: dat:HRM2_18920 CcmC2; PFAM: cytochrome c assembly protein; SPTR: C0QBY1 CcmC2; TIGRFAM: cytochrome c-type biogenesis protein CcsB; PFAM: Cytochrome C assembly protein; TIGRFAM: cytochrome c-type biogenesis protein CcsB.
  
    0.919
Deba_3044
InterPro IPR017941; KEGG: dal:Dalk_0333 Rieske (2Fe-2S) domain protein; PFAM: Rieske [2Fe-2S] iron-sulphur domain; SPTR: B8F910 Rieske (2Fe-2S) domain protein; PFAM: Rieske [2Fe-2S] domain.
  
  
 0.912
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
 
  
 0.876
Deba_2470
KEGG: ppd:Ppro_1254 cytochrome c assembly protein; SPTR: A1ANF5 Cytochrome c assembly protein; PFAM: Cytochrome C assembly protein.
  
    0.866
Deba_0816
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016:IPR014017:IPR000212; KEGG: dma:DMR_07030 ATP-dependent DNA helicase; PFAM: UvrD/REP helicase; SPTR: Q1NUA0 UvrD/REP helicase; PFAM: UvrD/REP helicase.
  
 
 0.859
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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