STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0837Ribonuclease BN; COGs: COG1295 membrane protein; InterPro IPR017039:IPR004664; KEGG: gme:Gmet_2779 ribonuclease BN; PFAM: ribonuclease BN; SPTR: Q39RX7 Ribonuclease BN; TIGRFAM: ribonuclease BN; PFAM: Ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN). (451 aa)    
Predicted Functional Partners:
Deba_0836
Methyltransferase-16, putative; InterPro IPR019410; KEGG: sfu:Sfum_0452 methyltransferase type 12; PFAM: Methyltransferase-16, putative; SPTR: C0GTM9 Methyltransferase small; PFAM: Putative methyltransferase.
     
 0.798
ade
COGs: COG1001 Adenine deaminase; InterPro IPR006679:IPR011059:IPR006680; KEGG: dma:DMR_21960 adenine deaminase; PFAM: amidohydrolase; PRIAM: Adenine deaminase; SPTR: C4XSJ0 Adenine deaminase; TIGRFAM: adenine deaminase; PFAM: Amidohydrolase family; TIGRFAM: adenine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
       0.666
Deba_0840
Protein of unknown function DUF490; COGs: COG2911 conserved hypothetical protein; InterPro IPR007452; KEGG: rce:RC1_3925 hypothetical protein; PFAM: protein of unknown function DUF490; SPTR: B6IY93 Putative uncharacterized protein; PFAM: Family of unknown function (DUF490).
 
     0.603
Deba_0835
DNA polymerase beta domain protein region; COGs: COG1669 nucleotidyltransferase; InterPro IPR002934; KEGG: cyn:Cyan7425_1203 DNA polymerase beta domain protein region; PFAM: DNA polymerase beta domain protein region; SPTR: B8HMG8 DNA polymerase beta domain protein region; PFAM: Nucleotidyltransferase domain.
       0.536
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
     
 0.522
Deba_0839
Surface antigen (D15); COGs: COG0729 Outer membrane protein; InterPro IPR010827:IPR000184; KEGG: sfu:Sfum_0758 surface antigen (D15); PFAM: surface antigen (D15); surface antigen variable number repeat protein; SPTR: A0LGA4 Surface antigen (D15); PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: outer membrane protein assembly complex, YaeT protein.
     
 0.508
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.505
Deba_2645
Protein-tyrosine phosphatase, low molecular weight; COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867; KEGG: dma:DMR_01880 putative arsenate reductase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: C4XG99 Putative arsenate reductase; PFAM: Low molecular weight phosphotyrosine protein phosphatase; TIGRFAM: arsenate reductase (thioredoxin).
  
  
 0.462
Deba_2647
Protein-tyrosine phosphatase, low molecular weight; COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867; KEGG: dvl:Dvul_1440 protein tyrosine phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: C0GLM6 Protein tyrosine phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase; TIGRFAM: arsenate reductase (thioredoxin).
  
  
 0.462
Deba_3024
DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477:IPR004797; KEGG: dal:Dalk_2782 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: B8FKV2 DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
 
   
 0.452
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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