STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0857COGs: COG1639 signal transduction protein; InterPro IPR013976; KEGG: aeh:Mlg_1873 diguanylate cyclase; PFAM: Metal-dependent hydrolase HDOD; SPTR: Q0A7H0 Diguanylate cyclase; PFAM: HDOD domain. (372 aa)    
Predicted Functional Partners:
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
   
 
 0.530
lexA
Transcriptional repressor, LexA family; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
       0.480
flgH
Flagellar L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
 
     0.470
flgI
Flagellar P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
 
     0.463
Deba_0855
KEGG: cdl:CDR20291_0586 hypothetical protein; SPTR: B0PCE4 Putative uncharacterized protein; PFAM: Pathogenicity locus.
       0.441
Deba_2686
KEGG: ilo:IL0280 hypothetical protein; SPTR: Q5QUM7 Uncharacterized conserved protein; PFAM: SprA-related family.
  
     0.407
Deba_2312
COGs: COG1868 Flagellar motor switch protein; InterPro IPR001543:IPR001689; KEGG: dma:DMR_22580 flagellar motor switch protein FliM; PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein; SPTR: C4XSQ7 Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM; PFAM: Surface presentation of antigens (SPOA); Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM.
 
    0.403
flgK
COGs: COG1256 Flagellar hook-associated protein; InterPro IPR002371:IPR001444:IPR010810:IPR010930; KEGG: dal:Dalk_0987 flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; flagellin hook IN repeat protein; flagellar basal body rod protein; SPTR: B8FK15 Flagellar hook-associated protein FlgK; TIGRFAM: flagellar hook-associated protein FlgK; PFAM: Flagellin hook IN motif; Flagella basal body rod protein; Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK.
 
    0.402
Deba_2330
COGs: COG4786 Flagellar basal body rod protein; InterProIPR019776:IPR001444:IPR010930:IPR020013:IPR 012834; KEGG: dvm:DvMF_2518 flagellar basal body rod protein FlgG; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; SPTR: B8DN17 Flagellar basal-body rod protein FlgG; TIGRFAM: flagellar basal-body rod protein FlgG; fagellar hook-basal body protein; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: fagellar hook-basal body proteins; flagellar basal-body rod protein FlgG, Gram-negative bacteria.
 
    0.400
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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