STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0902Protein of unknown function DUF111; COGs: COG1641 conserved hypothetical protein; InterPro IPR002822; KEGG: gsu:GSU0141 hypothetical protein; PFAM: protein of unknown function DUF111; SPTR: Q74GV3 UPF0272 protein GSU0141; PFAM: Protein of unknown function DUF111; TIGRFAM: conserved hypothetical protein TIGR00299; Belongs to the LarC family. (387 aa)    
Predicted Functional Partners:
Deba_1477
Conserved hypothetical protein; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR005232:IPR014729; KEGG: pca:Pcar_2431 hypothetical protein; SPTR: Q3A1T7 Putative uncharacterized protein; PFAM: Asparagine synthase; TIGRFAM: conserved hypothetical protein TIGR00268.
  
 0.937
Deba_2300
1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase; COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: gem:GM21_3730 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: C6E6X1 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PFAM: AIR carboxylase.
 
  
 0.931
Deba_0774
Protein of unknown function DUF2088; COGs: COG3875 conserved hypothetical protein; InterPro IPR018657; KEGG: afu:AF0049 hypothetical protein; PFAM: Protein of unknown function DUF2088; SPTR: O30187 Putative uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2088).
 
  
 0.857
lon
ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
       0.780
Deba_2634
4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG2768 Uncharacterized Fe-S center protein; InterPro IPR017900:IPR001450:IPR017896; KEGG: dol:Dole_2297 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A8ZV11 4Fe-4S ferredoxin iron-sulfur binding domain protein.
 
    0.603
Deba_0414
Protein of unknown function DUF362; COGs: COG2006 conserved hypothetical protein; InterPro IPR007160:IPR001450:IPR017896:IPR017900; KEGG: gsu:GSU0494 iron-sulfur cluster-binding protein; PFAM: protein of unknown function DUF362; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: C1TQG7 Uncharacterized conserved protein; PFAM: 4Fe-4S binding domain; Domain of unknown function (DUF362).
 
     0.517
Deba_0898
Peptidase M16 domain protein; COGs: COG0612 Zn-dependent peptidase; InterProIPR011237:IPR011249:IPR011765:IPR007863:IPR 001431; KEGG: gem:GM21_2975 peptidase M16 domain protein; PFAM: peptidase M16 domain protein; SPTR: C6E2P4 Peptidase M16 domain protein; PFAM: Peptidase M16 inactive domain; Insulinase (Peptidase family M16); Belongs to the peptidase M16 family.
       0.509
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
       0.509
Deba_0900
Beta-lactamase; COGs: COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I; KEGG: gme:Gmet_1944 beta-lactamase-like; SPTR: C8QYE7 Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily.
       0.509
Deba_1641
Cobalamin (vitamin B12) biosynthesis CbiM protein; COGs: COG0310 ABC-type Co2+ transport system permease component; InterPro IPR002751; KEGG: dvl:Dvul_1936 cobalt transport protein CbiM; PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; SPTR: A1VET6 Cobalamin (Vitamin B12) biosynthesis CbiM protein; PFAM: Cobalt uptake substrate-specific transmembrane region; TIGRFAM: cobalamin biosynthesis protein CbiM.
  
    0.495
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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