STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
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[Homology]
Score
Deba_0904Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068:IPR008978; KEGG: dol:Dole_2643 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: A8ZX67 Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family. (153 aa)    
Predicted Functional Partners:
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
 
 
 0.910
Deba_0903
Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068:IPR008978; KEGG: dol:Dole_2642 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: A8ZX66 Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; Belongs to the small heat shock protein (HSP20) family.
 
   
0.875
Deba_2571
ATP-binding region ATPase domain protein; InterPro IPR003594; KEGG: sfu:Sfum_3853 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; SPTR: A0LQ20 Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
 
 0.626
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.588
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.576
dnaK-2
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.576
rplP
Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
  
 
 0.575
hslV
20S proteasome A and B subunits; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
   
  
 0.563
Deba_3031
KEGG: gvi:glr2966 hypothetical protein; SPTR: Q7NCL2 Glr2966 protein.
  
 
 0.561
Deba_1146
COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146:IPR014746:IPR004809; KEGG: sat:SYN_01628 glutamine synthetase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; SPTR: Q2LXX3 Glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I.
    
 
 0.534
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.