STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (476 aa)    
Predicted Functional Partners:
mtaD
Amidohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.
 
 
 0.925
Deba_0376
Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680:IPR011059; KEGG: sat:SYN_01991 chlorohydrolase/deaminase family protein; PFAM: amidohydrolase; SPTR: Q2LUH4 5-methylthioadenosine/S-adenosylhomocysteine deaminase 2; PFAM: Amidohydrolase family.
 
 
 0.925
Deba_2578
DNA-cytosine methyltransferase; COGs: COG0270 Site-specific DNA methylase; InterPro IPR001525:IPR018117; KEGG: sfu:Sfum_3845 DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; SPTR: A0LQ12 DNA-cytosine methyltransferase; TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; TIGRFAM: DNA-methyltransferase (dcm); Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
    
 0.909
Deba_3155
NIL domain protein; InterPro IPR018449:IPR001450:IPR017896:IPR017900; KEGG: dev:DhcVS_791 iron-sulfur cluster-binding protein, ferredoxin-like protein; PFAM: NIL domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A8CNW3 4Fe-4S ferredoxin, iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain; NIL domain.
     
  0.900
Deba_3156
Protein of unknown function DUF39; COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: deh:cbdb_A872 hypothetical protein; PFAM: protein of unknown function DUF39; SPTR: Q3ZXP8 Putative uncharacterized protein; PFAM: Domain of unknown function DUF39.
     
  0.900
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
 
 
 0.893
Deba_1178
COGs: COG0031 Cysteine synthase; InterPro IPR001926:IPR005856:IPR005859; KEGG: dal:Dalk_2651 cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; SPTR: B8FIV3 Cysteine synthase A; TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases.
  
 0.859
Deba_1382
COGs: COG0460 Homoserine dehydrogenase; InterProIPR005106:IPR001342:IPR002912:IPR019811:IPR 016204:IPR016040; KEGG: gsu:GSU1693 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein; SPTR: Q74CI0 Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain.
   
 
 0.836
Deba_2205
KEGG: deb:DehaBAV1_0492 hypothetical protein; SPTR: A5FRU6 Putative uncharacterized protein; PFAM: Cobalamin-independent synthase, Catalytic domain.
  
  
 0.698
Deba_0872
KEGG: dal:Dalk_2588 hypothetical protein; SPTR: B8FIP0 Putative uncharacterized protein.
  
  
 0.681
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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