STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panDAspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (129 aa)    
Predicted Functional Partners:
panC
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
 
 0.999
panB
3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
 
  
 0.957
Deba_1258
COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterProIPR015590:IPR001670:IPR018211:IPR016160:IPR 016162:IPR016161; KEGG: dal:Dalk_3586 aldehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; iron-containing alcohol dehydrogenase; SPTR: B8FGP4 Aldehyde Dehydrogenase; PFAM: Aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase.
    
 0.918
Deba_0026
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
    
 0.840
Deba_1734
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR015424:IPR004839:IPR015421:IPR015422:IPR 001176:IPR004838; KEGG: dal:Dalk_0567 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: B8FHI5 Aminotransferase class I and II; PFAM: Aminotransferase class I and II.
    
 0.825
Deba_1979
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR004838:IPR001176:IPR004839:IPR015424:IPR 015421; KEGG: rsd:TGRD_536 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: B1H0I7 Aspartate aminotransferase; PFAM: Aminotransferase class I and II.
    
 0.825
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
    
  0.815
pyrB
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterProIPR002082:IPR006130:IPR019825:IPR006132:IPR 006131; KEGG: dol:Dole_0514 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: A8ZU12 Aspartate carbamoyltransferase; TIGRFAM: aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: as [...]
    
  0.805
argG
COGs: COG0137 Argininosuccinate synthase; InterPro IPR018223:IPR001518:IPR014729; KEGG: dal:Dalk_0409 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: B8FH30 Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
     
  0.800
Deba_3080
COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterProIPR006426:IPR000583:IPR001962:IPR017932:IPR 014729; KEGG: rrs:RoseRS_4439 asparagine synthase (glutamine-hydrolyzing); PFAM: asparagine synthase; glutamine amidotransferase class-II; PRIAM: Asparagine synthase (glutamine-hydrolyzing); SPTR: A5V1L8 Asparagine synthase (Glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing).
     
  0.800
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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