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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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tsaDMetalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (351 aa)    
Predicted Functional Partners:
Deba_0945
Protein of unknown function UPF0079; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: sat:SYN_02780 ATP/GTP hydrolase; PFAM: protein of unknown function UPF0079; SPTR: Q2LTJ6 ATP/GTP hydrolase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: conserved hypothetical nucleotide-binding protein.
 
 0.996
Deba_0748
Peptidase M22 glycoprotease; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: dps:DP1162 glycoprotein endopeptidase; PFAM: peptidase M22 glycoprotease; SPTR: Q6AP33 Related to glycoprotein endopeptidase; PFAM: Glycoprotease family.
 
 
 0.963
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
  
 0.914
fbp
Inositol phosphatase/fructose-16-bisphosphatase; COGs: COG0158 Fructose-1 6-bisphosphatase; InterPro IPR000146:IPR020548; KEGG: dvm:DvMF_0404 fructose-1,6-bisphosphatase; PFAM: Inositol phosphatase/fructose-16-bisphosphatase; SPTR: C0GQU0 Inositol phosphatase/fructose-16-bisphosphatase; PFAM: Fructose-1-6-bisphosphatase.
     
 0.828
Deba_2694
Sua5/YciO/YrdC/YwlC family protein; COGs: COG0009 Putative translation factor (SUA5); InterPro IPR004388:IPR017945:IPR006070; KEGG: sfu:Sfum_2120 SUA5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SPTR: A0LK51 Translation factor SUA5; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family.
 
 0.717
Deba_0167
Sua5/YciO/YrdC/YwlC family protein; COGs: COG0009 Putative translation factor (SUA5); InterPro IPR006070:IPR017945:IPR004388; KEGG: ank:AnaeK_1405 SUA5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SPTR: Q1NKA5 Sua5/YciO/YrdC/YwlC; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; Belongs to the SUA5 family.
 
 0.716
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
   
 
 0.670
panC
Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
    0.647
cysS-2
Cysteine synthase; COGs: COG0215 Cysteinyl-tRNA synthetase; InterProIPR005856:IPR002308:IPR001926:IPR009080:IPR 015803:IPR015273:IPR014729:IPR001216; KEGG: dal:Dalk_3820 cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; SPTR: B8FC88 Cysteine synthase; TIGRFAM: cysteine synthase; cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Str [...]
 
   
 0.619
Deba_1685
ABC transporter related protein; COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR003593:IPR000515:IPR003439:IPR017871; KEGG: dsa:Desal_1875 binding-protein-dependent transport systems inner membrane component; PFAM: ABC transporter related; binding-protein-dependent transport systems inner membrane component; SMART: AAA ATPase; SPTR: C6BUC7 Binding-protein-dependent transport systems inner membrane component; PFAM: ABC transporter; Binding-protein-dependent transport system inner membrane component.
 
   
 0.606
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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