STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nnrDCarbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] (525 aa)    
Predicted Functional Partners:
Deba_2577
Helicase domain protein; COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR014001:IPR001650:IPR000330:IPR014021; KEGG: sfu:Sfum_3846 helicase domain-containing protein; PFAM: helicase domain protein; SNF2-related protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: A0LQ13 Helicase domain protein; manually curated; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.
  
 0.923
Deba_0945
Protein of unknown function UPF0079; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: sat:SYN_02780 ATP/GTP hydrolase; PFAM: protein of unknown function UPF0079; SPTR: Q2LTJ6 ATP/GTP hydrolase; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: conserved hypothetical nucleotide-binding protein.
 
 
 0.913
Deba_0509
NUDIX hydrolase; InterPro IPR000086:IPR015797:IPR020084; KEGG: rmr:Rmar_0039 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: D0MK35 NUDIX hydrolase; PFAM: NUDIX domain; Belongs to the Nudix hydrolase family.
  
 0.895
Deba_0930
NUDIX hydrolase; InterPro IPR015797:IPR000086; KEGG: rde:RD1_0410 hydrolase, putative; PFAM: NUDIX hydrolase; SPTR: Q16D17 Hydrolase, putative; PFAM: NUDIX domain.
  
 0.895
pdxJ
Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
     
 0.867
acpS
Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
       0.861
ybeY
Protein of unknown function UPF0054; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
       0.859
Deba_0951
PhoH family protein; COGs: COG1702 Phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714; KEGG: dal:Dalk_3324 PhoH family protein; PFAM: PhoH family protein; SPTR: B8FJ86 PhoH family protein; PFAM: PhoH-like protein.
       0.858
Deba_0950
7TM receptor with intracellular metal dependent phosphohydrolase; COGs: COG1480 membrane-associated HD superfamily hydrolase; InterPro IPR011621:IPR006674:IPR006675:IPR003607; KEGG: dol:Dole_0778 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; metal-dependent phosphohydrolase 7TM intracellular region; SMART: metal-dependent phosphohydrolase HD region; SPTR: A8ZVC7 Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; 7TM receptor with intracellular HD hydrolase; TIGRFAM: ATP synthase subunit 6 (eukaryotes),a [...]
       0.853
rhlB
DEAD/DEAH box helicase domain protein; DEAD-box RNA helicase involved in RNA degradation. Has RNA- dependent ATPase activity and unwinds double-stranded RNA.
  
 0.842
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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