STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
cbiACobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (470 aa)    
Predicted Functional Partners:
Deba_2457
Precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: dba:Dbac_0965 precorrin-8X methylmutase CbiC/CobH; PFAM: Precorrin-8X methylmutase CbiC/CobH; PRIAM: Precorrin-8X methylmutase; SPTR: C0GRL7 Precorrin-8X methylmutase CbiC/CobH; PFAM: Precorrin-8X methylmutase.
 
 0.989
Deba_1099
Aminotransferase class I and II; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR015424:IPR004839:IPR015421; KEGG: gme:Gmet_0487 L-threonine O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: Q39YE4 L-threonine O-3-phosphate decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase.
  
 0.947
Deba_0870
cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
 
 
 0.940
Deba_2517
Cobaltochelatase; COGs: COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatase; InterPro IPR003006:IPR003672; KEGG: ppd:Ppro_1259 cobaltochelatase; PFAM: CobN/magnesium chelatase; PRIAM: Cobaltochelatase; SPTR: A1ANG0 Hydrogenobyrinic acid a,c-diamide cobaltochelatase; PFAM: CobN/Magnesium Chelatase; TIGRFAM: cobaltochelatase, CobN subunit.
 
 
 0.938
Deba_2469
Cobaltochelatase; COGs: COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatase; InterPro IPR003672; KEGG: dal:Dalk_4060 cobaltochelatase; PFAM: CobN/magnesium chelatase; PRIAM: Cobaltochelatase; SPTR: B8FM12 Cobaltochelatase; PFAM: CobN/Magnesium Chelatase; TIGRFAM: cobaltochelatase, CobN subunit.
 
 
 0.937
Deba_2516
Magnesium chelatase; COGs: COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatase; InterPro IPR003672; KEGG: cts:Ctha_2441 cobaltochelatase; PFAM: CobN/magnesium chelatase; PRIAM: Magnesium chelatase; SPTR: B3QX80 Cobaltochelatase; PFAM: CobN/Magnesium Chelatase.
 
 
 0.935
cbiA-2
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
  
 
0.914
Deba_2460
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR012818:IPR014008:IPR000878:IPR006365; KEGG: dvl:Dvul_0558 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PRIAM: Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); SPTR: A1VAW5 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; precorrin-6y C5,15-methyltransferase (d [...]
  
 0.910
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.890
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
 0.861
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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