STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_0998COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR001501:IPR018194; KEGG: dps:DP0159 cytochrome-c3 hydrogenase (NiFeSe), large subunit; PFAM: nickel-dependent hydrogenase large subunit; PRIAM: Cytochrome-c3 hydrogenase; SPTR: Q6ARY7 Related to cytochrome-c3 hydrogenase (NiFeSe), large subunit; PFAM: Nickel-dependent hydrogenase. (500 aa)    
Predicted Functional Partners:
Deba_0997
COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterProIPR001821:IPR019546:IPR006137:IPR016160:IPR 017909:IPR006311; KEGG: dps:DP0160 periplasmic [NiFeSe] hydrogenase, small subunit [precursor]; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; Twin-arginine translocation pathway, signal sequence, subgroup; PRIAM: Hydrogenase (acceptor); SPTR: Q6ARY6 Related to periplasmic [NiFeSe] hydrogenase, small subunit [Precursor]; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: Tat (twin-arginine translocation) pathway signal seq [...]
 
 
 0.996
Deba_1400
COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterPro IPR006137:IPR001821:IPR017909:IPR006311; KEGG: dal:Dalk_2275 hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; PRIAM: Cytochrome-c3 hydrogenase; SPTR: B8FIH8 Hydrogenase (NiFe) small subunit HydA; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence; hydrogenase (NiFe) small subunit (hydA).
 
 
 0.984
Deba_0984
Methyl-viologen-reducing hydrogenase delta subunit; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterProIPR013027:IPR004792:IPR001450:IPR003813:IPR 017900:IPR017896; KEGG: adg:Adeg_1078 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; HI0933 family protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: C9RD78 Methyl-viologen-reducing hydrogenase delta subunit; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit; Pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.968
Deba_0787
Methyl-viologen-reducing hydrogenase delta subunit; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR017896:IPR001450:IPR003813; KEGG: dal:Dalk_2269 methyl-viologen-reducing hydrogenase delta subunit; PFAM: methyl-viologen-reducing hydrogenase delta subunit; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: B8FIH2 Methyl-viologen-reducing hydrogenase delta subunit; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit.
  
 
 0.960
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.917
Deba_0887
COGs: COG1035 Coenzyme F420-reducing hydrogenase beta subunit; InterProIPR017896:IPR001450:IPR007516:IPR007525:IPR 017900; KEGG: dal:Dalk_2982 coenzyme F420 hydrogenase; PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; PRIAM: Coenzyme F420 hydrogenase; SPTR: B8FL37 Coenzyme F420 hydrogenase; PFAM: Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term; Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus.
  
 
 0.907
Deba_1402
COGs: COG0680 Ni Fe-hydrogenase maturation factor; InterPro IPR000671; KEGG: sfu:Sfum_2951 hydrogenase expression/formation protein; PFAM: peptidase M52 hydrogen uptake protein; SPTR: A0LMH3 Hydrogenase expression/formation protein; TIGRFAM: hydrogenase maturation protease; PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase expression/formation protein; hydrogenase maturation protease.
 
 
 0.905
Deba_2740
Hydrogenase expression/formation protein HypD; COGs: COG0409 Hydrogenase maturation factor; InterPro IPR002780; KEGG: glo:Glov_3063 hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; SPTR: B6G9X3 Putative uncharacterized protein; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
 
 0.832
Deba_1403
Hydrogenase assembly chaperone hypC/hupF; COGs: COG0298 Hydrogenase maturation factor; InterPro IPR001109; KEGG: dal:Dalk_2278 hydrogenase assembly chaperone HypC/HupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); SPTR: B8FII1 Hydrogenase assembly chaperone hypC/hupF; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF.
 
 
 0.811
Deba_2741
(NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
 
 
 0.784
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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