STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_1008COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterProIPR013105:IPR011717:IPR011990:IPR019734:IPR 013026; KEGG: cbh:CLC_2580 hypothetical protein; PFAM: Tetratricopeptide TPR_2 repeat protein; Tetratricopeptide TPR_4; SPTR: C6PUP8 Putative uncharacterized protein. (586 aa)    
Predicted Functional Partners:
Deba_0455
Undecaprenyl-phosphate glucose phosphotransferase; COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362:IPR016040:IPR017473:IPR017475; KEGG: mxa:MXAN_2922 sugar transferase; PFAM: sugar transferase; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Q1PWC3 Similar to capsular polysaccharide synthesis protein; TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: Bacterial sugar transferase; TIGRFAM: Undecaprenyl-phosphate glucose phosphotransferase; e [...]
  
  
 0.716
glgB
1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
  
 0.691
Deba_3097
Tetratricopeptide TPR_2 repeat protein; InterProIPR001440:IPR013105:IPR019734:IPR013026:IPR 011990; KEGG: dat:HRM2_20780 tetratricopeptide (TPR) domain protein; PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SPTR: C0QDB3 Tetratricopeptide (TPR) domain protein; PFAM: ChAPs (Chs5p-Arf1p-binding proteins); TIGRFAM: putative PEP-CTERM system TPR-repeat lipoprotein.
  
 
 0.684
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
  
 
 0.675
Deba_0674
Putative enzyme (3.4.-); COGs: COG1073 Hydrolase of the alpha/beta superfamily; KEGG: pca:Pcar_2424 putative enzyme (3.4.-); SPTR: Q3A1U4 Putative enzyme (3.4.-); PFAM: Prolyl oligopeptidase family; Putative lysophospholipase.
   
 
 0.577
Deba_2291
COGs: COG1898 dTDP-4-dehydrorhamnose 3 5-epimerase; InterPro IPR011051:IPR014710:IPR000888; KEGG: sat:SYN_00576 dTDP-4-dehydrorhamnose 3,5-epimerase; SPTR: Q2LVW0 DTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: WxcM-like, C-terminal.
  
  
 0.567
Deba_1678
Polysaccharide biosynthesis protein; COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797:IPR002229; KEGG: gbm:Gbem_1791 polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; SPTR: B5EAA1 Polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein.
 
  
 0.556
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 
 0.548
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
  
 0.546
Deba_2421
Oxidoreductase domain protein; COGs: COG0673 dehydrogenase and related protein; InterPro IPR016040:IPR011004:IPR000683:IPR001451; KEGG: cbc:CbuK_0696 NAD-dependent oxidoreductase; PFAM: oxidoreductase domain protein; transferase hexapeptide repeat containing protein; SPTR: B6J6Q3 NAD-dependent oxidoreductase; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Bacterial transferase hexapeptide (three repeats).
  
  
 0.544
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.