STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_1134Heavy metal translocating P-type ATPase; COGs: COG2217 Cation transport ATPase; InterProIPR001757:IPR001366:IPR008250:IPR005834:IPR 018303:IPR000150:IPR006404:IPR006416; KEGG: dma:DMR_28780 putative cation translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: C4XHJ5 Putative cation translocating P-type ATPase; TIGRFAM: heavy metal translocating P-type ATPase; cadmium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase [...] (634 aa)    
Predicted Functional Partners:
Deba_2004
InterPro IPR000428:IPR006121; KEGG: dal:Dalk_3004 heavy metal transport/detoxification protein; PFAM: Heavy metal transport/detoxification protein; SPTR: B8FL59 Heavy metal transport/detoxification protein; PFAM: Heavy-metal-associated domain.
  
 
 0.892
Deba_2382
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.551
Deba_2270
Transcriptional regulator, ArsR family; COGs: COG0640 transcriptional regulator protein; InterPro IPR001845:IPR011991; KEGG: dal:Dalk_3679 transcriptional regulator, ArsR family; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: B8FLL3 Transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family.
 
  
 0.489
Deba_1133
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873:IPR020845; KEGG: afw:Anae109_1649 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: A7HAV7 AMP-dependent synthetase and ligase; PFAM: AMP-binding enzyme.
  
    0.467
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.453
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.451
dnaK-2
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.445
Deba_2508
ABC transporter related protein; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR017871:IPR003593:IPR011527:IPR001140:IPR 003439:IPR017940; KEGG: nha:Nham_3544 ABC transporter, ATP-binding/permease protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: Q0FX25 ABC multidrug efflux transporter, fused ATPase and inner membrane subunits; PFAM: ABC transporter transmembrane region; ABC transporter.
 
   
 0.433
Deba_2482
ABC transporter related protein; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR017871:IPR003593:IPR011527:IPR001140:IPR 003439:IPR017940; KEGG: cbf:CLI_1144 ABC transport ATP-binding/permease protein; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: B1Q7H1 ABC transport ATP-binding/permease protein; PFAM: ABC transporter transmembrane region; ABC transporter.
 
   
 0.405
Deba_2997
DSBA oxidoreductase; COGs: COG1651 Protein-disulfide isomerase; InterPro IPR001853:IPR012335:IPR012336; KEGG: dma:DMR_06250 DsbA oxidoreductase family protein; PFAM: DSBA oxidoreductase; SPTR: C4XIV2 DSBA oxidoreductase family protein.
 
 
 
 0.401
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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