STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_1152COGs: COG0069 Glutamate synthase domain 2; InterProIPR002489:IPR000583:IPR006982:IPR002932:IPR 013785:IPR017932; KEGG: ttr:Tter_0474 glutamate synthase (ferredoxin); PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: D1CEN9 Glutamate synthase (Ferredoxin); PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II. (1528 aa)    
Predicted Functional Partners:
Deba_0487
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterProIPR019575:IPR013027:IPR009051:IPR012285:IPR 016040:IPR000759:IPR001949; KEGG: dds:Ddes_1543 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: B8J118 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; manually curated; PFAM: Pyridine nucleotide-disulphide oxidoreductase; NADH-u [...]
 
 0.999
Deba_1151
Glutamate synthase, NADH/NADPH, small subunit; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterProIPR000759:IPR009051:IPR013027:IPR012285:IPR 016040:IPR006005; KEGG: mva:Mvan_5697 glutamate synthase subunit beta; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: A1TH12 Glutamate synthase (NADH) small subunit; TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthases, NADH/NADPH, small subunit.
 0.999
rnfB
Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
 
 0.999
Deba_2226
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterProIPR009051:IPR000759:IPR016040:IPR017896:IPR 017900:IPR001450:IPR013027:IPR003953; KEGG: dal:Dalk_3266 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: B8FJ29 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: Pyridine nucle [...]
 
 
 0.999
rnfB-2
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
 
 0.999
Deba_1146
COGs: COG0174 Glutamine synthetase; InterPro IPR008147:IPR008146:IPR014746:IPR004809; KEGG: sat:SYN_01628 glutamine synthetase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; SPTR: Q2LXX3 Glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I.
  
 
 0.988
Deba_0692
COGs: COG0069 Glutamate synthase domain 2; InterPro IPR013785:IPR002932; KEGG: ate:Athe_2034 ferredoxin-dependent glutamate synthase; PFAM: ferredoxin-dependent glutamate synthase; SPTR: B9MLC1 Ferredoxin-dependent glutamate synthase; PFAM: Conserved region in glutamate synthase.
  
 
 0.982
carB
COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR016185:IPR005480:IPR005481:IPR 005479:IPR011607:IPR011761:IPR005483:IPR013817:IPR013816; KEGG: sfu:Sfum_0008 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: C8R2N3 Carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase [...]
  
 
 0.979
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.971
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
   
 0.970
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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