STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Deba_1167Radical SAM domain protein; COGs: COG0731 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: hha:Hhal_2049 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: C8R0D6 Radical SAM domain protein; PFAM: Radical SAM superfamily. (315 aa)    
Predicted Functional Partners:
pcm
protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
  
    0.670
obg
GTP-binding protein Obg/CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
 
 
    0.661
Deba_1166
Dihydrouridine synthase DuS; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
  
  
 0.589
ispH
Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
       0.544
Deba_2175
Cobyrinic acid ac-diamide synthase; COGs: COG1149 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain; InterPro IPR017896:IPR017900:IPR002586:IPR001450; KEGG: sfu:Sfum_3408 cobyrinic acid a,c-diamide synthase; PFAM: Cobyrinic acid ac-diamide synthase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A0LNS9 Cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
 
     0.542
Deba_2176
Cobyrinic acid ac-diamide synthase; COGs: COG1149 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain; InterPro IPR017896:IPR017900:IPR002586:IPR001450; KEGG: sfu:Sfum_3409 cobyrinic acid a,c-diamide synthase; PFAM: Cobyrinic acid ac-diamide synthase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A0LNT0 Cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; 4Fe-4S binding domain.
 
     0.506
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
    0.492
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
    0.489
Deba_1168
Protein of unknown function DUF1555; InterPro IPR011449:IPR013424; KEGG: pat:Patl_1971 agarase; PFAM: protein of unknown function DUF1555; SPTR: B9ZJM7 Putative uncharacterized protein; TIGRFAM: PEP-CTERM putative exosortase interaction domain.
       0.476
Deba_2177
COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: dds:Ddes_1867 dinitrogenase iron-molybdenum cofactor biosynthesis protein; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; SPTR: Q5DUA6 Putative uncharacterized protein orp (Fragment); PFAM: Dinitrogenase iron-molybdenum cofactor.
 
     0.460
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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