STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
Deba_1088
COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterProIPR009051:IPR001041:IPR017900:IPR012675:IPR 012285:IPR017896:IPR004489; KEGG: bpt:Bpet1823 succinate dehydrogenase iron-sulfur subunit; PRIAM: Succinate dehydrogenase (ubiquinone); SPTR: C1SJU7 Succinate dehydrogenase subunit B; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein.
 
 0.988
Deba_1089
COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterProIPR015939:IPR003953:IPR004112:IPR003952:IPR 011281:IPR014006; KEGG: apt:APA01_00330 succinate dehydrogenase flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: C1SJU6 Succinate dehydrogenase subunit A; TIGRFAM: succinate dehydrogenase, flavoprotein subunit; succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase, flavoprotein subunit, E. coli/mitochondrial subgroup; su [...]
 
 0.985
Deba_1491
COGs: COG0372 Citrate synthase; InterProIPR002020:IPR019810:IPR016142:IPR010953:IPR 016141; KEGG: dal:Dalk_4974 citrate synthase I; PFAM: Citrate synthase; PRIAM: Citrate (Si)-synthase; SPTR: B8FDL5 Citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); Belongs to the citrate synthase family.
  
 
 0.982
Deba_1090
COGs: COG2142 Succinate dehydrogenase hydrophobic anchor subunit; InterPro IPR000701:IPR014312; KEGG: cts:Ctha_0457 succinate dehydrogenase, membrane subunit, putative; PFAM: succinate dehydrogenase cytochrome b subunit; SPTR: B3QUM2 Succinate dehydrogenase, membrane subunit, putative; TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit; TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein.
  
 
 0.979
Deba_1091
InterPro IPR000701:IPR014314:IPR014312; KEGG: rmr:Rmar_0208 succinate dehydrogenase, cytochrome b556 subunit; PFAM: succinate dehydrogenase cytochrome b subunit; SPTR: D0MD04 Succinate dehydrogenase, cytochrome b556 subunit; TIGRFAM: succinate dehydrogenase, cytochrome b556 subunit; succinate dehydrogenase, hydrophobic membrane anchor protein; PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit; TIGRFAM: succinate dehydrogenase, hydrophobic membrane anchor protein; succinate dehydrogenase, cytochrome b556 subunit.
  
 
 0.979
Deba_1038
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002869:IPR009014:IPR019752:IPR002880; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; SPTR: B8DNT7 Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase.
  
 
 0.954
Deba_2851
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880:IPR015941:IPR009014:IPR005829; KEGG: sfu:Sfum_1166 2-oxoglutarate ferredoxin oxidoreductase subunit alpha; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: A0LHF7 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit; PFAM: domain.
 
 
 0.937
Deba_0710
COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR003702; KEGG: mhu:Mhun_1561 acetyl-CoA hydrolase/transferase; PFAM: acetyl-CoA hydrolase/transferase; SPTR: Q2FRF0 Acetyl-CoA hydrolase/transferase; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain.
   
 0.932
Deba_1953
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880:IPR009014:IPR015941; KEGG: gme:Gmet_1307 2-ketoisovalerate ferredoxin reductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: Q39W31 Pyruvate flavodoxin/ferredoxin oxidoreductase-like; PFAM: domain.
  
 
 0.927
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.