STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_1211Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR001714:IPR000994:IPR000587; KEGG: sfu:Sfum_0169 peptidase M24; PFAM: peptidase M24; creatinase; SPTR: Q1NY97 Peptidase M24; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain. (365 aa)    
Predicted Functional Partners:
Deba_1209
Polynucleotide adenylyltransferase region; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR001667:IPR003156:IPR000644:IPR002646; KEGG: sfu:Sfum_0679 polynucleotide adenylyltransferase region; PFAM: Polynucleotide adenylyltransferase region; CBS domain containing protein; phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SMART: CBS domain containing protein; SPTR: A0LG26 Polynucleotide adenylyltransferase region; PFAM: DHH family; DHHA1 domain; CBS domain; Poly A polymerase head domain; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
       0.821
xerC
Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
     
 0.812
Deba_1205
Pseudouridine synthase; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterProIPR020103:IPR002942:IPR006145:IPR018496:IPR 000748; KEGG: adg:Adeg_1292 pseudouridine synthase; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: C9R7X1 Pseudouridine synthase; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase family; Belongs to the pseudouridine synthase RsuA family.
 
     0.808
Deba_1206
Chromosome segregation and condensation protein, ScpB; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
       0.794
Deba_1207
Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
     
 0.793
Deba_1208
Peptidase M50; COGs: COG1994 Zn-dependent protease; InterPro IPR008915; KEGG: dps:DP0062 hypothetical protein; PFAM: peptidase M50; SPTR: Q6ASD4 Conserved hypothetical membrane protein; PFAM: Peptidase family M50.
  
    0.793
aroQ
3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
 
    0.707
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
  
 
 0.690
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.677
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
 
 0.642
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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