Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Deba_1225COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003594:IPR011006; KEGG: lic:LIC11110 histidine kinase response regulator hybrid protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; SMART: response regulator receiver; SPTR: Q8F227 Two-component hybrid sensor and regulator; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. (288 aa)    
Predicted Functional Partners:
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
 
 
0.960
Deba_1226
COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001789:IPR010822:IPR001932:IPR011006; KEGG: hmo:HM1_2362 response regulator receiver modulated serine phosphatase; PFAM: Stage II sporulation E family protein; response regulator receiver; SMART: protein phosphatase 2C domain protein; response regulator receiver; SPTR: B0TIH1 Response regulator receiver modulated serine phosphatase; PFAM: Response regulator receiver domain; Stage II sporulation protein E (SpoIIE).
 
 
0.946
Deba_1234
Anti-sigma-factor antagonist; InterPro IPR002645; KEGG: pca:Pcar_1874 anti-anti-sigma regulatory factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Q1NPE5 Sulfate transporter/antisigma-factor antagonist STAS; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor.
 
 
 0.919
Deba_3291
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR000014:IPR003594:IPR009082:IPR003018:IPR 013656:IPR003661:IPR005467:IPR004358; KEGG: cau:Caur_1383 PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; SPTR: A9W9X5 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF do [...]
 
 
 0.878
Deba_2322
RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterProIPR013325:IPR013324:IPR000943:IPR011991:IPR 007627:IPR007624:IPR007630:IPR014284:IPR012845; KEGG: mgm:Mmc1_3037 FliA/WhiG family RNA polymerase sigma factor; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; SPTR: A0LC35 RNA polymerase, sigma 28 subunit, FliA/WhiG family; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; S [...]
  
 
 0.858
Deba_1490
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013656:IPR003661:IPR003594:IPR005467:IPR 000014:IPR000700:IPR004358:IPR001610:IPR009082; KEGG: dma:DMR_41550 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; PAC repeat-containing protein; PAS domain containing protein; histidine kinase A domain protein; SPTR: C4XPU6 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phos [...]
 
 
 0.853
Deba_0030
COGs: COG0642 Signal transduction histidine kinase; InterProIPR013656:IPR003661:IPR003594:IPR005467:IPR 000014:IPR009082:IPR004358; KEGG: cag:Cagg_2683 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: B8G4S5 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS [...]
 
 
 0.852
Deba_3210
COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003594:IPR009082:IPR013767:IPR 003661:IPR005467:IPR004358; KEGG: dma:DMR_23810 putative sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: C4XT75 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS [...]
 
 
 0.851
Deba_0349
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR013767:IPR003661:IPR003594:IPR009082:IPR 000014:IPR004358:IPR005467; KEGG: sfu:Sfum_2495 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: A0LL72 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-l [...]
 
 
 0.849
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
  
0.849
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.