STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_1234Anti-sigma-factor antagonist; InterPro IPR002645; KEGG: pca:Pcar_1874 anti-anti-sigma regulatory factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Q1NPE5 Sulfate transporter/antisigma-factor antagonist STAS; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor. (102 aa)    
Predicted Functional Partners:
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
 
  
 0.947
Deba_1225
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003594:IPR011006; KEGG: lic:LIC11110 histidine kinase response regulator hybrid protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; SMART: response regulator receiver; SPTR: Q8F227 Two-component hybrid sensor and regulator; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.923
Deba_1226
COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001789:IPR010822:IPR001932:IPR011006; KEGG: hmo:HM1_2362 response regulator receiver modulated serine phosphatase; PFAM: Stage II sporulation E family protein; response regulator receiver; SMART: protein phosphatase 2C domain protein; response regulator receiver; SPTR: B0TIH1 Response regulator receiver modulated serine phosphatase; PFAM: Response regulator receiver domain; Stage II sporulation protein E (SpoIIE).
 
 
 0.876
Deba_2006
COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR003594; KEGG: mem:Memar_2469 putative anti-sigma regulatory factor, serine/threonine protein kinase; PFAM: ATP-binding region ATPase domain protein; SPTR: D1JH80 Putative uncharacterized protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.823
Deba_2858
COGs: COG2233 Xanthine/uracil permease; InterPro IPR006043:IPR018062; KEGG: pth:PTH_2271 xanthine/uracil permeases; PFAM: Xanthine/uracil/vitamin C permease; SPTR: A5CZY9 Xanthine/uracil permeases; PFAM: Permease family; TIGRFAM: uracil-xanthine permease.
  
 
 0.816
Deba_1612
Putative PAS/PAC sensor protein; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterProIPR000014:IPR001932:IPR013656:IPR010822:IPR 000700; KEGG: gme:Gmet_2818 putative PAS/PAC sensor protein; PFAM: Stage II sporulation E family protein; PAS fold-4 domain protein; SMART: protein phosphatase 2C domain protein; PAS domain containing protein; SPTR: C8QVW1 Putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: Stage II sporulation protein E (SpoIIE); PAS fold; TIGRFAM: PAS domain S-box.
 
 
 0.811
Deba_2265
COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR016196:IPR003594:IPR011701; KEGG: bbe:BBR47_11350 hypothetical protein; PFAM: major facilitator superfamily MFS_1; ATP-binding region ATPase domain protein; SPTR: C0Z6F5 Conserved hypothetical membrane protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Major Facilitator Superfamily.
  
 
 0.811
Deba_1524
COGs: COG2172 Anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR003594; KEGG: dth:DICTH_0761 anti-sigma regulatory factor; PFAM: ATP-binding region ATPase domain protein; SPTR: C1TN97 Anti-sigma regulatory factor (Ser/Thr protein kinase); PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
  
 
 0.800
Deba_1233
Putative anti-anti-sigma factor; InterPro IPR002645; KEGG: xca:xccb100_1462 putative anti-anti-sigma factor; SPTR: Q8P7B2 Putative uncharacterized protein.
     
 0.770
Deba_3182
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR004010:IPR003660:IPR010822:IPR001932; KEGG: dma:DMR_08680 putative phosphatase; PFAM: Stage II sporulation E family protein; histidine kinase HAMP region domain protein; Cache domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase HAMP region domain protein; SPTR: C4XK04 Putative phosphatase; PFAM: HAMP domain; Cache domain; Stage II sporulation protein E (SpoIIE).
 
 
 0.757
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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