STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_1240Transferase hexapeptide repeat protein; COGs: COG0663 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR001451:IPR011004; KEGG: ank:AnaeK_1516 transferase hexapeptide repeat protein; SPTR: B4UK37 Transferase hexapeptide repeat protein; manually curated. (179 aa)    
Predicted Functional Partners:
Deba_1241
KEGG: sfu:Sfum_1244 hypothetical protein; SPTR: A0LHN4 Putative uncharacterized protein.
       0.789
Deba_0557
COGs: COG0288 Carbonic anhydrase; InterPro IPR001765; KEGG: pca:Pcar_2939 carbonic anhydrase; PFAM: carbonic anhydrase; SPTR: Q3A0D3 Carbonic anhydrase; PFAM: Carbonic anhydrase.
    
 
 0.786
Deba_1239
Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047:IPR011055; KEGG: sat:SYN_00940 peptidoglycan-specific endopeptidase, M23 family; PFAM: Peptidase M23; SPTR: Q1NUT6 Peptidase M23B; PFAM: Peptidase family M23.
       0.551
pyrC
Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
  
 0.507
folE2
GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate.
  
  
 0.499
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.478
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
    0.417
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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