Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rpoDRNA polymerase, sigma 70 subunit, RpoD subfamily; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (590 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.970
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.967
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.944
Deba_3269
RNA polymerase, sigma 32 subunit, RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
  
 
0.910
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
 
 
 0.880
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
  
 0.879
Deba_0731
COGs: COG1329 Transcriptional regulators similar to M. xanthus CarD; InterPro IPR003711; KEGG: dal:Dalk_3372 transcriptional regulator, CarD family; PFAM: transcription factor CarD; SPTR: B8FLB5 Transcriptional regulator, CarD family; PFAM: CarD-like/TRCF domain.
   
 
 0.795
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
 
 
 0.775
Deba_1295
COGs: COG2378 transcriptional regulator protein; KEGG: sat:SYN_02988 transcriptional regulator; SPTR: Q2LX17 Transcriptional regulator.
    
   0.763
Deba_1550
COGs: COG3264 Small-conductance mechanosensitive channel; InterProIPR000595:IPR018490:IPR011066:IPR010920:IPR 006685:IPR014710; KEGG: mxa:MXAN_2799 mechanosensitive ion channel/cyclic nucleotide-binding domain-containing protein; PFAM: MscS Mechanosensitive ion channel; cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: B5II47 Mechanosensitive ion channel/cyclic nucleotide-binding domain protein; PFAM: Mechanosensitive ion channel; Cyclic nucleotide-binding domain.
   
 
 0.747
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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