STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lapBTPR repeat-containing protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. (405 aa)    
Predicted Functional Partners:
Deba_1299
KEGG: drt:Dret_1341 hypothetical protein; SPTR: C8X2I2 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1049).
 
   
 0.885
lpxC
UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
   
 
 0.818
Deba_1298
Histidine triad (HIT) protein; COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310:IPR011151:IPR011146; KEGG: sfu:Sfum_2126 histidine triad (HIT) protein; PFAM: histidine triad (HIT) protein; SPTR: A0LK57 Histidine triad (HIT) protein; PFAM: HIT domain.
       0.818
Deba_1296
ApbE family lipoprotein; COGs: COG2122 conserved hypothetical protein; InterPro IPR003374:IPR007183; KEGG: sfu:Sfum_2124 hypothetical protein; PFAM: ApbE family lipoprotein; SPTR: A0LK55 Putative uncharacterized protein; PFAM: ApbE family.
       0.762
Deba_1297
Phosphodiesterase, MJ0936 family; COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR000979; KEGG: dal:Dalk_0913 phosphodiesterase, MJ0936 family; PFAM: metallophosphoesterase; SPTR: Q2YZQ0 Putative uncharacterized protein; TIGRFAM: phosphodiesterase, MJ0936 family; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family.
       0.753
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
       0.626
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
   
 
 0.604
Deba_1302
Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: drt:Dret_0142 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: C8WZG9 N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes.
     
 0.584
Deba_2329
COGs: COG4786 Flagellar basal body rod protein; InterProIPR019776:IPR001444:IPR010930:IPR020013:IPR 012836; KEGG: geo:Geob_0627 flagellar basal-body rod protein FlgF; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; SPTR: B9M0F5 Flagellar basal-body rod protein FlgF; TIGRFAM: flagellar basal-body rod protein FlgF; fagellar hook-basal body protein; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgF; fagellar hook-basal body proteins.
    
   0.487
Deba_0479
COGs: COG0077 Prephenate dehydratase; InterProIPR020822:IPR001086:IPR002912:IPR008242:IPR 002701:IPR018528; KEGG: pca:Pcar_1887 chorismate mutase-P and prephenate dehydratase; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Q1K0T9 Chorismate mutase; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
 
   
 0.445
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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