Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Deba_1364COGs: COG0694 Thioredoxin-like protein and domains; InterPro IPR001075; KEGG: sat:SYN_02452 NifU-like domain-containing protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: C0GLY6 Nitrogen-fixing NifU domain protein; PFAM: NifU-like domain. (73 aa)    
Predicted Functional Partners:
Deba_1088
COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterProIPR009051:IPR001041:IPR017900:IPR012675:IPR 012285:IPR017896:IPR004489; KEGG: bpt:Bpet1823 succinate dehydrogenase iron-sulfur subunit; PRIAM: Succinate dehydrogenase (ubiquinone); SPTR: C1SJU7 Succinate dehydrogenase subunit B; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein.
  
 
 0.815
lipB-2
Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives; Belongs to the LipB family.
  
 0.773
iscS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
 
 0.714
purC
COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR001636:IPR018236:IPR013816; KEGG: glo:Glov_3047 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: B3E940 Phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase.
  
    0.713
Deba_1363
COGs: COG3920 Signal transduction histidine kinase; InterPro IPR003594; KEGG: tro:trd_0267 probable two component sensor kinase; PFAM: ATP-binding region ATPase domain protein; SPTR: B9KXS9 Probable two component sensor kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; HWE histidine kinase.
       0.705
Deba_0689
Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
  
 
 0.702
ilvD
COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR000581:IPR004404:IPR020558; KEGG: mja:MJ1276 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: C5U5V1 Dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 
 0.635
Deba_2129
HesB/YadR/YfhF-family protein; InterPro IPR000361; KEGG: dal:Dalk_4032 hypothetical protein; PFAM: HesB/YadR/YfhF-family protein; SPTR: B8FLY4 Putative uncharacterized protein; PFAM: Iron-sulphur cluster biosynthesis.
  
 
 0.631
Deba_2810
InterPro IPR000361; KEGG: dps:DP0988 hypothetical protein; PFAM: HesB/YadR/YfhF-family protein; SPTR: Q6APK7 Putative uncharacterized protein; PFAM: Iron-sulphur cluster biosynthesis.
  
 
 0.631
Deba_2811
HesB/YadR/YfhF-family protein; Contains Selenocysteine; InterPro IPR000361; KEGG: dsa:Desal_0629 HesB/YadR/YfhF-family protein; PFAM: HesB/YadR/YfhF-family protein; SPTR: C6BYA4 HesB/YadR/YfhF-family protein; manually curated; PFAM: Iron-sulphur cluster biosynthesis.
  
 
 0.631
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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