STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_1369Thioredoxin domain-containing protein; InterPro IPR012335:IPR012336; KEGG: sfu:Sfum_3604 thioredoxin domain-containing protein; SPTR: A0LPC2 Thioredoxin domain; PFAM: Thioredoxin. (125 aa)    
Predicted Functional Partners:
Deba_2650
COGs: COG4232 Thiol:disulfide interchange protein; InterPro IPR003834; KEGG: dol:Dole_2887 cytochrome c biogenesis protein transmembrane region; PFAM: cytochrome c biogenesis protein transmembrane region; SPTR: Q30XL8 Putative uncharacterized protein; PFAM: Cytochrome C biogenesis protein transmembrane region.
 
 
 0.954
Deba_0595
Protein-disulfide reductase; COGs: COG4232 Thiol:disulfide interchange protein; InterPro IPR003834:IPR012336:IPR012335:IPR017936; KEGG: sfu:Sfum_2885 cytochrome c biogenesis protein, transmembrane region; PFAM: cytochrome c biogenesis protein transmembrane region; PRIAM: Protein-disulfide reductase; SPTR: C0GMD4 Cytochrome c biogenesis protein transmembrane region; PFAM: Thioredoxin; Cytochrome C biogenesis protein transmembrane region.
  
 
 0.801
Deba_2010
KEGG: sus:Acid_5380 hypothetical protein; SPTR: Q01VI6 Putative uncharacterized protein; PFAM: Disulphide bond corrector protein DsbC.
  
 
 0.798
Deba_0693
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR004099:IPR016156:IPR013027:IPR000815:IPR 012999; KEGG: rxy:Rxyl_1767 mercuric reductase MerA; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: B4D639 Pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
  
 0.738
Deba_2198
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR016156:IPR013027:IPR000815:IPR004099:IPR 012999:IPR006258; KEGG: dsa:Desal_3027 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: C6C0Y2 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
  
 0.738
Deba_2981
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027:IPR004099:IPR000815:IPR016156:IPR 012999:IPR006258; KEGG: mta:Moth_1763 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: A1HU83 Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
  
 0.738
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.720
Deba_0400
Conserved hypothetical protein; InterPro IPR011009:IPR000719; KEGG: dsa:Desal_2316 hypothetical protein; SPTR: C6BWU2 Putative uncharacterized protein.
  
 
 
 0.694
Deba_2759
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 
 0.663
Deba_1137
COGs: COG0492 Thioredoxin reductase; InterPro IPR000103:IPR013027:IPR005982; KEGG: pth:PTH_1417 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: A5D2B9 Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
  
 
 0.649
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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