STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_1384Thioesterase superfamily protein; COGs: COG0824 thioesterase; InterPro IPR006683:IPR006684; KEGG: ade:Adeh_1639 4-hydroxybenzoyl-CoA thioesterase; PFAM: thioesterase superfamily protein; SPTR: Q2IID3 4-hydroxybenzoyl-CoA thioesterase; PFAM: Thioesterase superfamily; TIGRFAM: conserved hypothetical protein TIGR00051; tol-pal system-associated acyl-CoA thioesterase. (136 aa)    
Predicted Functional Partners:
Deba_1383
Proposed homoserine kinase; COGs: COG3635 phosphoglycerate mutase AP superfamily; InterProIPR019304:IPR006124:IPR004456:IPR013371:IPR 017850; KEGG: pca:Pcar_1514 cofactor-independent phosphoglycerate mutase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; metalloenzyme domain protein; PRIAM: Phosphoglycerate mutase; SPTR: Q3A4E7 Phosphoglycerate mutase; TIGRFAM: proposed homoserine kinase; phosphonopyruvate decarboxylase-related protein; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Metalloenzyme superfamily; TIGRFAM: 2,3-bisphosphoglycerate-inde [...]
       0.795
Deba_1955
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterProIPR014043:IPR016035:IPR016036:IPR001227:IPR 004410; KEGG: dal:Dalk_3440 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; SPTR: B8FLI2 Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
 
 
 0.773
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.718
Deba_1382
COGs: COG0460 Homoserine dehydrogenase; InterProIPR005106:IPR001342:IPR002912:IPR019811:IPR 016204:IPR016040; KEGG: gsu:GSU1693 homoserine dehydrogenase; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; amino acid-binding ACT domain protein; SPTR: Q74CI0 Homoserine dehydrogenase; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain.
       0.716
Deba_1381
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterProIPR004839:IPR004838:IPR015421:IPR015422:IPR 015424; KEGG: sfu:Sfum_1219 aminotransferase, class I and II; PFAM: aminotransferase class I and II; SPTR: A0LHK9 Aminotransferase; PFAM: Aminotransferase class I and II.
       0.639
Deba_1292
COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753:IPR018376; KEGG: chy:CHY_1601 3-hydroxybutyryl-CoA dehydratase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: C0GKR8 Enoyl-CoA hydratase/isomerase; PFAM: Enoyl-CoA hydratase/isomerase family; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.611
Deba_0913
COGs: COG1536 Flagellar motor switch protein; InterPro IPR000090:IPR011002; KEGG: dba:Dbac_3030 flagellar motor switch protein FliG; PFAM: flagellar motor switch protein FliG; SPTR: C0GRQ1 Flagellar motor switch protein FliG; TIGRFAM: flagellar motor switch protein FliG; PFAM: FliG C-terminal domain; TIGRFAM: flagellar motor switch protein FliG.
    
   0.560
Deba_2322
RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterProIPR013325:IPR013324:IPR000943:IPR011991:IPR 007627:IPR007624:IPR007630:IPR014284:IPR012845; KEGG: mgm:Mmc1_3037 FliA/WhiG family RNA polymerase sigma factor; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; SPTR: A0LC35 RNA polymerase, sigma 28 subunit, FliA/WhiG family; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; S [...]
    
   0.560
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
   
   0.553
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
 
 0.537
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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