STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Deba_1385Pyruvate, phosphate dikinase; COGs: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterProIPR002192:IPR008279:IPR000121:IPR018274:IPR 010121:IPR013815:IPR013816:IPR015813; KEGG: gsu:GSU0580 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; PRIAM: Pyruvate, phosphate dikinase; SPTR: Q74FM6 Pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate phosphate dikinase, PEP/py [...] (894 aa)    
Predicted Functional Partners:
Deba_2141
Malic protein NAD-binding protein; COGs: COG0281 Malic enzyme; InterProIPR016040:IPR015884:IPR012188:IPR012301:IPR 012302:IPR002505; KEGG: glo:Glov_1262 malic enzyme; PFAM: malic protein NAD-binding; malic protein domain protein; phosphate acetyl/butaryl transferase; SPTR: B3E7A4 Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase; PFAM: Malic enzyme, NAD binding domain; Phosphate acetyl/butaryl transferase; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase.
  
 
 0.944
Deba_1038
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002869:IPR009014:IPR019752:IPR002880; KEGG: dvm:DvMF_0184 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; SPTR: B8DNT7 Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase.
    
 0.921
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
    
 0.919
Deba_1368
Conserved carboxylase region; COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891:IPR003379:IPR013785; KEGG: dat:HRM2_31800 Pcb; PFAM: Conserved carboxylase region; pyruvate carboxyltransferase; SPTR: C0QLF7 Pcb; PFAM: HMGL-like; Conserved carboxylase domain.
    
 0.916
Deba_1395
COGs: COG0469 Pyruvate kinase; InterProIPR015793:IPR015794:IPR015813:IPR001697:IPR 015795:IPR011037; KEGG: gau:GAU_1104 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PRIAM: Pyruvate kinase; SPTR: Q1K4D5 Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.914
Deba_3203
COGs: COG1144 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase delta subunit; InterPro IPR011898:IPR001450:IPR017896:IPR017900; KEGG: sfu:Sfum_2793 pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: A0LM19 Pyruvate ferredoxin oxidoreductase, delta subunit; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S binding domain; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family.
    
 0.912
Deba_3201
Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: sfu:Sfum_2795 thiamine pyrophosphate binding domain-containing protein; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: A0LM21 Pyruvate ferredoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
    
 0.911
Deba_1037
COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766:IPR011896; KEGG: drt:Dret_0516 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; PRIAM: 2-oxoglutarate synthase; SPTR: C8X0I8 Pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: Pyruvate ferredoxin oxidoreductase beta subunit C terminal; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; T [...]
    
 0.910
Deba_1952
Thiamine pyrophosphate protein domain protein TPP-binding protein; COGs: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase beta subunit; InterPro IPR011766; KEGG: gur:Gura_2238 thiamine pyrophosphate binding domain-containing protein; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: A5G3Q3 Thiamine pyrophosphate enzyme domain protein TPP-binding; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain.
    
 0.910
Deba_1953
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880:IPR009014:IPR015941; KEGG: gme:Gmet_1307 2-ketoisovalerate ferredoxin reductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: Q39W31 Pyruvate flavodoxin/ferredoxin oxidoreductase-like; PFAM: domain.
    
 0.910
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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