STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Deba_1407COGs: COG0328 Ribonuclease HI; InterPro IPR002156:IPR012337; KEGG: mxa:MXAN_5728 ribonuclease H; PFAM: ribonuclease H; SPTR: Q098P5 RNase H; PFAM: RNase H. (202 aa)    
Predicted Functional Partners:
Deba_1408
Protein of unknown function DUF164; COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: sfu:Sfum_1209 hypothetical protein; PFAM: protein of unknown function DUF164; SPTR: A0LHK0 Putative uncharacterized protein; PFAM: Putative zinc ribbon domain.
  
  
 0.927
Deba_0360
Phosphoglycerate mutase; COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: gur:Gura_4185 phosphoglycerate mutase; PFAM: Phosphoglycerate mutase; SPTR: A5G960 Phosphoglycerate mutase; PFAM: Phosphoglycerate mutase family; TIGRFAM: alpha-ribazole phosphatase.
 
  
 0.912
Deba_1409
Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678:IPR017221:IPR011322; KEGG: sth:STH598 hypothetical protein; PFAM: protein of unknown function DUF34; SPTR: Q67RW0 Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
  
  
 0.903
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
 
 
 0.829
rnhB
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
   
 
 0.809
Deba_1106
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
   
 
 0.801
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.666
Deba_1290
COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR013767:IPR003018:IPR013656:IPR 003661:IPR003594:IPR008207:IPR005467:IPR000014:IPR000700:I PR004358:IPR001610:IPR011006:IPR009082; KEGG: dvm:DvMF_1096 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold domain protein; GAF domain protein; PAS fold-4 domain protein; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS domain con [...]
  
  
 0.629
Deba_1209
Polynucleotide adenylyltransferase region; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR001667:IPR003156:IPR000644:IPR002646; KEGG: sfu:Sfum_0679 polynucleotide adenylyltransferase region; PFAM: Polynucleotide adenylyltransferase region; CBS domain containing protein; phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SMART: CBS domain containing protein; SPTR: A0LG26 Polynucleotide adenylyltransferase region; PFAM: DHH family; DHHA1 domain; CBS domain; Poly A polymerase head domain; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
  
 0.605
Deba_1477
Conserved hypothetical protein; COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR005232:IPR014729; KEGG: pca:Pcar_2431 hypothetical protein; SPTR: Q3A1T7 Putative uncharacterized protein; PFAM: Asparagine synthase; TIGRFAM: conserved hypothetical protein TIGR00268.
 
      0.605
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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