STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Deba_1409Protein of unknown function DUF34; COGs: COG0327 conserved hypothetical protein; InterPro IPR002678:IPR017221:IPR011322; KEGG: sth:STH598 hypothetical protein; PFAM: protein of unknown function DUF34; SPTR: Q67RW0 Putative uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486; Belongs to the GTP cyclohydrolase I type 2/NIF3 family. (384 aa)    
Predicted Functional Partners:
Deba_1408
Protein of unknown function DUF164; COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: sfu:Sfum_1209 hypothetical protein; PFAM: protein of unknown function DUF164; SPTR: A0LHK0 Putative uncharacterized protein; PFAM: Putative zinc ribbon domain.
  
  
 0.918
Deba_1407
COGs: COG0328 Ribonuclease HI; InterPro IPR002156:IPR012337; KEGG: mxa:MXAN_5728 ribonuclease H; PFAM: ribonuclease H; SPTR: Q098P5 RNase H; PFAM: RNase H.
  
    0.831
Deba_1099
Aminotransferase class I and II; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR015424:IPR004839:IPR015421; KEGG: gme:Gmet_0487 L-threonine O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: Q39YE4 L-threonine O-3-phosphate decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase.
  
  
 0.787
hisC
COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterProIPR005861:IPR001917:IPR015421:IPR015422:IPR 015424:IPR004839; KEGG: sfu:Sfum_2116 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: A0LK47 Histidinol phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
 0.787
Deba_0175
COGs: COG2049 Allophanate hydrolase subunit 1; InterPro IPR003833:IPR003778:IPR010016; KEGG: sth:STH379 putative allophanate hydrolase; PFAM: Allophanate hydrolase subunit 1; Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 1; Allophanate hydrolase subunit 2; SPTR: Q67SH9 Putative allophanate hydrolase; PFAM: Metallo-beta-lactamase superfamily; Allophanate hydrolase subunit 2; Allophanate hydrolase subunit 1; TIGRFAM: conserved hypothetical protein TIGR00370; biotin-dependent carboxylase uncharacterized domain.
  
  
 0.742
Deba_2288
dTDP-glucose 4,6-dehydratase; COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR016040:IPR002198:IPR001509:IPR005888; KEGG: rpd:RPD_1571 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Q13AT1 dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
    0.644
Deba_0748
Peptidase M22 glycoprotease; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: dps:DP1162 glycoprotein endopeptidase; PFAM: peptidase M22 glycoprotease; SPTR: Q6AP33 Related to glycoprotein endopeptidase; PFAM: Glycoprotease family.
 
   
 0.555
nfo
Apurinic endonuclease Apn1; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
     
 0.539
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
       0.534
purE
Phosphoribosylamine/glycine ligase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR); Belongs to the GARS family.
       0.531
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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