Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Deba_1430Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR016040:IPR002347; KEGG: sfu:Sfum_0112 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: A0LEG3 Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase. (263 aa)    
Predicted Functional Partners:
Deba_1955
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterProIPR014043:IPR016035:IPR016036:IPR001227:IPR 004410; KEGG: dal:Dalk_3440 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; SPTR: B8FLI2 Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
 
 0.960
Deba_2386
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 0.950
fabZ
Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
 
 0.935
fabH
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
  
 
 0.930
Deba_2388
3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  
 
0.922
Deba_1432
ABC transporter related protein; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR001140:IPR003439:IPR017871:IPR017940:IPR 003593:IPR011527; KEGG: dal:Dalk_3748 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: B8FLT1 ABC transporter related; PFAM: ABC transporter transmembrane region; ABC transporter.
 
 
 0.845
Deba_1431
ABC transporter related protein; COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterProIPR001140:IPR003439:IPR017871:IPR017940:IPR 003593:IPR011527; KEGG: dal:Dalk_3747 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: B8FLT0 ABC transporter related; PFAM: ABC transporter transmembrane region; ABC transporter.
 
 
 0.843
Deba_1433
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COGs: COG0526 Thiol-disulfide isomerase and thioredoxins; InterPro IPR000866:IPR017936:IPR012335:IPR012336; KEGG: rmr:Rmar_1898 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: D0MJX3 Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; PFAM: AhpC/TSA family.
     
 0.781
Deba_2969
KEGG: bcv:Bcav_3932 hypothetical protein; SPTR: C5C533 Putative uncharacterized protein.
   
 0.620
Deba_2144
COGs: COG0777 Acetyl-CoA carboxylase beta subunit; InterPro IPR000438:IPR011762:IPR011763:IPR000022; KEGG: gsu:GSU2370 acetyl-CoA carboxylase, carboxyl transferase, beta subunit; PFAM: carboxyl transferase; SPTR: Q74AI4 Acetyl-CoA carboxylase, carboxyl transferase, beta subunit; PFAM: Carboxyl transferase domain; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit.
 
  
 0.617
Your Current Organism:
Desulfarculus baarsii
NCBI taxonomy Id: 644282
Other names: D. baarsii DSM 2075, Desulfarculus baarsii 2st 14, Desulfarculus baarsii DSM 2075, Desulfarculus baarsii str. DSM 2075, Desulfarculus baarsii strain DSM 2075
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